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Remeron Tapering

Remeron Tapering

This entry was posted in Antidepressant on by .

Last Updated on March 2, 2021 by Carol Gillette

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Alternative to Meds Editorial Team
Written by Lyle Murphy
Medically Reviewed by Dr Samuel Lee MD

Alternative to Meds Center offers safe and comfortable Remeron tapering programs. Using antidepressants can quickly devolve into a nightmare of such suffering that even the most unread in the medical field have now begun waking up to the severity of the problem. Most physicians do not know how to help.

One of the more popular reasons for stopping Remeron is because its side effects begin to outweigh any perceived benefits. Getting off Remeron may be the only logical choice where the drug has so often utterly failed in expected treatment results.

Do you feel misunderstood?
You are not alone.

remeron titration
Alternative to Meds has been the authority on Remeron tapering for more than 15 years. Our historical success is now documented in published evidence. Even if the person had what might be considered highly atypical symptoms, these same symptoms are much more common than one might think. The reason we specialize in these symptoms is that many of us trained professionals at the center have also had to endure them ourselves in order to become the effective helpers of others.
This video is of a woman who came to ATMC years ago in a highly compromised state. She could barely walk, was on benzos and antidepressants, and could not even imagine working as the professional she once was. She became medication-free, gained the ability to power walk easily, and she has been consistently working as a professional counselor now in the years since she has graduated.
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About Remeron Tapering

Many persons have been misdiagnosed. Misdiagnosis is arguably the most common reason for considering tapering from Remeron. Of particular note, the DSM V (prescribing manual) recently upgraded the necessary criteria that would indicate antidepressants as a valid treatment.

Thus, some patients had likely been put on Remeron in error, and now desire to begin weaning off Remeron because, to begin with, prescribed antidepressant medication wasn’t the right choice. 1

Remeron and PTSD

treatment for PTSDOne example revolves around PTSD. The criteria for diagnosing a person with PTSD have changed a few times. A diagnosis of PTSD may have been hasty or premature. Some exclusions might be where a person has experienced death in the family, or when a close friend dies.1 Other examples of exclusions could be when symptoms are caused by medications, illness, or substance abuse. These would be (should be) exclusions. But often, these exclusions are missed entirely, hanging a person with a diagnosis that is not accurate, and a drug that will not help. Remeron tapering may be indicated especially where the accuracy of a PTSD diagnosis was unclear or incorrect.

If you feel you may have been prescribed antidepressant medication unnecessarily, you may wish to speak about it further with your prescribing physician. One can find out more about what steps are needed for antidepressant tapering. It is recommended that a person not delay in seeking this medical assistance. This is because the longer one remains on medication, especially where it was not the correct treatment to begin with, the more complex the process of getting off Remeron can become.

Learning More About How to Get Off Remeron


In terms of side effects, there can be many of these and they may be different for each individual in character, and also intensity can vary widely.

Some side effects may be mild for one person, and intolerable for another. As seen below, there are mild, moderate, and severe or even life-threatening reactions to Remeron.

Below are just some examples of what may lead a person to choose to taper off Remeron.


Reasons to Consider Tapering From Remeron:

  • Mild side effects have begun negatively affecting the person’s quality of life, such as dry mouth, ulcers in the mouth, swelling of the lips or tongue, drooling, bleeding gums, loss of ability to taste, indigestion, altered sensations of taste, smell, etc.
  • A person may experience more serious health concerns such as vomiting, bleeding intestines, worsened depression, sleep disturbances, agitated. edgy or irritated feeling, shaking, flu-like symptoms (cough, fever, sore throat, headache), anger, twitching, restless legs, anxiety, back pain, muscle pain, etc.
  • Side effects have become extremely severe and in some cases may become life-threatening such as suicidality, akathisia, mania, confusion, pancreatitis, convulsion, stupor, and other severe adverse reactions.*
  • A woman who becomes pregnant or plans to become pregnant may be concerned regarding the increased chance of miscarriage and premature birth that occur among mothers taking Remeron during pregnancy.2

*More information on severe side effects available from FDA.

remeron tapering

Remeron Titration Should Never be Done Abruptly

brain reactionsThere can be many reasons for stopping Remeron; probably just about as many as there are individuals who started taking the drug. However, there is one point that is absolutely critical. And that is to avoid stopping Remeron abruptly. Weaning off Remeron safely requires a very gradual and gentle approach, with qualified medical oversight and monitoring throughout the process. With these cautions in place, Remeron titration can be successfully completed without lingering symptoms of discontinuation. One will suffer from lingering reactions especially where the process was done too quickly. The body needs to be allowed the time needed to adjust and normalize. Otherwise, it would be painful to endure.

Remeron Tapering Made Simpler, Safer, Easier to Tolerate

Alternative to Meds Center provides an amazingly comprehensive treatment program that consists of too many segments to describe in this short article. But there are 5 main categories into which these therapies are organized at Alternative to Meds Center, as follows:

  1. Neurotoxin testing and removal by non-invasive and natural methods such as low-temperature sauna, castor oil packs, nebulized glutathione, mineral detox foot baths, and many other treatments.
  2. Dietary and nutritional corrections, orthomolecular and environmental medicine, etc., for enhancing neurochemistry replacement and improved energy, mood, etc.
  3. Natural Remeron alternatives that effectively replace prescription medicine, handle sleep issues, etc. without toxic drugs.
  4. Therapies for physical pain relief and healing as well as to provide mental and emotional comfort such as Reiki, craniosacral massage, life coaching, CBT, equine-assisted therapy, soothing mineral baths, acupuncture, gentle exercise classes (trainer-led), stress reduction techniques, and many, many more.
  5. There is also an educational component to the program where clients learn about neurochemistry, diet and mood, how toxic food additives harm the CNS/brain, the gut-brain connection and how to protect it, and much more.

WARNING:  NEVER ABRUPTLY ATTEMPT STOPPING REMERON. EVEN THE FDA4 CAUTIONS THAT TO DO SO CAN RESULT IN SIGNIFICANT RISKS TO HEALTH. There are safer and more gradual ways that can ease the process of Remeron titration without endangering one’s health.3

Additional Notes on Remeron

help-for-depressionRemeron is an antidepressant drug in the tetracyclic class, meaning its atomic structure consists of 4 rings rather than the 3 rings or other variations in the chemical structure of other antidepressants. This is why, in part, Remeron is referred to as an “atypical” antidepressant, because it is believed that it has characteristics that are quite different from other types or classes of antidepressants. And, important to note, it is not known exactly how it creates the effects that it does in the brain and CNS.

Some studies show that physical changes to the brain occur over long-term use of antidepressants, and indicate that more research is needed.5 There are some indications suggesting Remeron affects the histamine receptors, adrenaline receptors plus dopamine, and serotonin receptors. But it is not exactly understood how these all interact exactly. At low doses, Remeron often has more of a sedative effect. At higher doses, the drug tends to have a stimulating effect. It is clear, the body of knowledge about antidepressants is far from complete.

How Long Does Remeron Tapering Take?

help getting off remeronThe Alternative to Meds Center Remeron tapering programs recommend that the client enrolls for 60 days, on average, although a longer stay can be arranged if requested. Our goal at the center is to provide the means for our clients to achieve natural mental health using holistic alternatives for prescription drugs. Clients are given a program that is designed to test for and address any possible factors that may have contributed to unwanted symptoms that were troubling the person before starting to take prescription medications. Remeron has a complex structure and side effect profile. Various potential interactions and reactions will be undergoing flux while a person attempts to normalize their neurochemistry during Remeron tapering. An adequate time frame in which to complete the Remeron cessation comfortably will be of great importance. The length of time for Remeron titration can vary, such as for a person who has already tried to quit but was balked by the intensity of withdrawals. The person will do much better with enough time allowed to safely complete their Remeron taper.

Alternative to Meds Center This approach is supported by nutritional testing and correction of deficiencies, neurotoxin testing and removal, and addressing many other factors that may have never been previously addressed, and that could have lead to seeking relief through unnecessary medication.

Please contact Alternative to Meds Center for a much more detailed description of our inpatient Remeron tapering programs and what benefits are available to our clients who wish to improve their mental health naturally.

1. Truschet E, “Depression Definition and DSM 5 Diagnostic Criteria” Remedy Health Media [INTERNET] 2019 Mar, updated 2019 Nov 25 [cited 2020 Jun 4].

2. “Exposure to mirtazapine during pregnancy, a prospective, comparative study of birth outcomes” Article published by US National Library of Medicine 2006 Aug, PubMed, [cited 2020 Jun 4].

3. Shelton R MD “Steps Following Attainment of Remission- Discontinuation of Antidepressant Therapy” US National Library of Medicine” [cited 2020 Jun 4].

4. FDA Label Remeron (mirtazapine)

5. Dusi N, Barlati S, Vita A, Brambilla P, “Brain Structural Effects of Antidepressant Treatment in Major Depression.” Current Neuropharmacology [Internet] 2015 [cited 2020 Sep 12]

This content has been reviewed and approved by a licensed physician.

Dr. Samuel Lee

Dr. Samuel Lee is a board-certified psychiatrist, specializing in a spiritually-based mental health discipline and integrative approaches. He graduated with an MD at Loma Linda University School of Medicine and did a residency in psychiatry at Cedars-Sinai Medical Center and University of Washington School of Medicine in Seattle. He has also been an inpatient adult psychiatrist at Kaweah Delta Mental Health Hospital and the primary attending geriatric psychiatrist at the Auerbach Inpatient Psychiatric Jewish Home Hospital. In addition, he served as the general adult outpatient psychiatrist at Kaiser Permanente.  He is board-certified in psychiatry and neurology and has a B.A. Magna Cum Laude in Religion from Pacific Union College. His specialty is in natural healing techniques that promote the body’s innate ability to heal itself.

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Nothing on this Website is intended to be taken as medical advice. The information provided on the website is intended to encourage, not replace, direct patient-health professional relationships. Always consult with your doctor before altering your medications. Adding nutritional supplements may alter the effect of medication. Any medication changes should be done only after proper evaluation and under medical supervision.

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