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Clonazepam Withdrawal Symptoms

Although Clonazepam is considered a long-acting benzodiazepine, it still needs to be tapered carefully and gradually enough to give the body time to adjust to a decreasing dose over time. There can be many adverse effects when coming off benzodiazepines. These drugs have been described as harder to withdraw from than heroin or other opiates.2,5

Some symptoms of clonazepam withdrawal:

  • Sleep disturbances, rebound insomnia, nightmares 7,8
  • Seizures, muscle spasms, tics, jerking motions, tremors*1,8,9,19
  • Suicidality, increased depression, dysphoria 1,8
  • Increased anxiety, panic attacks, rebound anxiety 1,7,8
  • Paranoia 8,19
  • Abnormal sense distortions, sensory hypersensitivity 8
  • Patches of numbness, tingling, heat or cold, itching, feelings of electric shock 19
  • Visual or perception disturbances, blurred vision, tilting walls or floors 7,8,19
  • Mania, delusions, hallucinations, delirium, psychotic reactions 1,7,8
  • Mood swings, irritability, hostility, aggressiveness, anger 1,8
  • Restlessness, compulsions, agitation, pacing, marching, etc.1,8
  • Faintness, dizziness, lightheadedness 8
  • Nausea, stomach pain, appetite changes, anorexia, dry retching 1,7,8
  • Confusion, mental fog, feeling disoriented especially in elderly patients 8
  • Feelings of unreality, depersonalization 8
  • Tinnitus 20
  • Shooting pains in the spine, neck, muscle pain 8
  • Stiffness/tension in neck, jaw, feet, hands, limbs, the back, scalp, forehead 8,19
  • Weakened immune system 19
  • Headache 7,8

*The FDA has issued warnings concerning the risk for status epilepticus1 that may emerge during withdrawal. Grand mal seizures have been documented with abrupt benzodiazepine withdrawal.8


Too many doctors and detox centers unwittingly let their patients down with mismanaged clonazepam withdrawal. Clonazepam ( Klonopin ) does not lend itself to a rapid withdrawal and the reduction needs to be done slowly, precisely, and compassionately.

Clonazepam, like all benzodiazepines, can manifest nasty withdrawal complications, often far worse than heroin. Yet, according to the DEA, as a schedule IV drug,6 Klonopin has “a low potential for abuse and low risk of dependence.” That would be laughable were it not such a tragic misrepresentation that then gets conveyed to unsuspecting patients.1

Do Your Symptoms Require Clonazepam?

clonazepam addiction withdrawal
Alternative to Meds has been a world expert on effective, safe benzodiazepine withdrawal for more than fifteen years. Our published evidence reflects an astounding 87.5% long-term success rate for our clients. In conjunction with slow tapering techniques, we use holistic supplementation, counseling, along with neurotoxin removal that assists the withdrawal and also provides lasting relief after the reduction is complete. While some people need only good tapering strategies, others are neurotoxic, meaning their neurochemistry may have gone into overdrive. Simply reducing the dose will not be enough to restore health. Techniques are needed that lessen that toxic burden before they can expect to find relief without the drugs. Each person’s profile has to be addressed in all its unique detail, and that is how we are able to effectively relieve and resolve these unwanted symptoms for long-lasting relief.

You are likely painfully aware of the horrors of this drug. Trying to navigate life on Klonopin can be a mess. Yet trying to get off of it can feel worse than death if it is done poorly. You probably feel trapped and feel no one understands your suffering. Then you sound just like we did … and that’s why we are doing this work.
Please watch the videos you see here or call us to get hope about your situation.

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What is Clonazepam (Klonopin) Used For?

Clonazepam or Klonopin is a prescribed medication in the benzodiazepine class, which the FDA describes as a long-acting, high potency benzodiazepine with anti-convulsive and anxiolytic, sedative properties.7,8 Clonazepam is FDA approved to treat seizure and panic disorders in adults and children.1

A number of off-label uses have also developed,13,14 examples of which are included below.

  • Panic Disorder (a psychiatric mental disorder characterized by unfounded terror episodes that can occur frequently and unexpectedly).
  • Seizure Disorders (any of a number of epilepsy conditions characterized by seizures)
  • Agoraphobia (an anxiety disorder characterized by something in the environment that triggers fear, where a person feels unsafe and unable to escape such as in a mall, subway, outside the home, etc. )
  • Lennox-Gastaut Syndrome (a type of epilepsy characterized by repeating seizures)
  • Absence Seizures (a type of epilepsy, also called petit mal seizures: short-lived seizures that cause a temporary blank-out, or staring into space for a few seconds)
  • Anxiety Disorders (a group of mental disorders characterized by episodes of stress, worry, and fretting, social anxiety disorder, etc.)
  • OCD (a psychiatric condition where a person feels compelled to repeat actions or words or patterns to avoid the anxiety that presents if these actions are not performed).
  • PTSD ( post-traumatic stress disorder, after an event characterized by terror, the threat of death, or similar, where these past events can be triggered in the present by certain environmental reminders, recreating the sense of terror or shock, etc., from the past experience.).
  • Mania (a psychiatric condition characterized by a flight of ideas, illusions, feelings of superhuman ability, euphoria, power, etc.)
  • Restless legs
  • Tardive Dyskinesia
  • Insomnia, REM sleep behavior disorder

Clonazepam (Klonopin) Alternative Names and Slang

According to the DEA, street names for benzodiazepines include “downers,” “nerve pills,” “tranks,” and “benzos.” Klonopin is one of the top five benzodiazepines available on the street. Other names for Klonopin according to the Dept. of Consumer Protection include “KPins,” “Pins,” “K-cuts,” or “super Valium” when sold on the street.15,16

The drug has become somewhat popularized not only as a fast-acting sedative drug, but also for its near-immediate euphoric effects, and is considered high risk for abuse and addiction. The broad medical consensus now advises that benzodiazepines should only be taken for short-term use because of their addictive properties. Recommendations from the Ashton research materials are to prescribe only 1-7 days’ worth or at maximum, 2-4 weeks’ worth.17

The British Journal of Pharmacology concurs and also advises that benzodiazepines should not be a first-line treatment choice, but where they are prescribed, they should only be used short-term.18

Many people have become inadvertently addicted to benzodiazepines such as Klonopin, and may even resort to obtaining them off the street in a desperate attempt to prevent the drug’s horrific withdrawals.15,16

Clonazepam Side Effects

The side effects of Klonopin can be quite severe and can discount any perceived benefits of the drug. It should only be used short-term for anxiety, as the side effects can become more formidable over time.

Common side effects of clonazepam (Klonopin)21-23 can include:

  • Respiratory depression, respiratory arrest
  • Depression
  • Increased anxiety
  • Euphoria
  • Flu-like symptoms, such as a runny nose, fever, diarrhea, etc.
  • Increased risk of Alzheimer’s disease
  • Increased risk of pneumonia in older adults and other age groups
  • Insomnia, disturbed sleep, strange dreams
  • Difficulty speaking, slurred speech
  • Slowed or difficult breathing
  • Unsteady or slow movements
  • Motor movement disorders, akathisia, restlessness, pacing, marching, rocking, etc.
  • Sedation, tiredness, drowsiness
  • Vision becomes blurred, double vision, cyclic eyelid movement, difficulty focusing
  • Headaches
  • Dry mouth
  • Excessive salivation
  • Reduced appetite
  • Sore gums
  • Constipation
  • Loss of orientation
  • Memory loss
  • Cognitive impairment
  • Confusion
  • Becomes disoriented

When Benzodiazepines are mixed with other CNS depressants such as opioids, alcohol, or others, the synergistic effects can become much more severe and can be fatal. The FDA has placed a black box warning on benzodiazepines to alert consumers of these medications.1

Discontinuing Clonazepam (Klonopin) Safely

Klonopin belongs to the benzodiazepine class of drugs. Clonazepam withdrawal should never be abrupt, or “cold turkey.” When this drug, like other similar medications, is withdrawn too abruptly, the withdrawal symptoms can become extremely harsh and intolerable. The result of coming off too fast is that some symptoms will linger far longer than necessary (as in protracted withdrawal) and can lead to relapse because of their intensity.

Recommended is to do a gentle taper from the drug under medical supervision. Benzodiazepines can cause seizures and even death from suddenly stopping, especially if the person has acclimated to using this medication over a long duration.1,17-19

When the time comes to begin the detox or tapering process, an inpatient treatment setting that can provide close and careful medical monitoring is recommended.

Clonazepam Withdrawal FAQs

Below we have collected pertinent information on clonazepam (Klonopin), and some frequently requested topics related to taking the drug, withdrawal from the drug, and other information.

What Does Clonazepam Do for Anxiety?

Klonopin can induce a calming sedation and can quickly reduce the intensity of a panic attack or anxiety episode. However, the drug’s effects are temporary and these unwanted symptoms may soon return and even intensify between doses. Benzodiazepines act on GABA receptors, but their exact mechanism is as yet unknown.24

Patients taking Klonopin at night may find that by the morning, the sedating effects may have worn off. For people with daytime anxiety, this can create a rollercoaster effect of between-dosing withdrawal manifestations, similar to antidepressant interdose withdrawals.25 The practitioner may be inclined to include daytime dosing. However, the person with anxiety could quickly find themselves in a spot where they are taking the medication two or three times a day, yet still suffering from symptoms more and more. Benzodiazepines should be taken for the short-term only, because of their decreasing efficacy and addictive potential.16-19

Benzodiazepines affect a neurotransmitter called GABA and the effect is a slowing or calming of the CNS. Benzodiazepines should never be mixed with alcohol, opiates, or other CNS depressants as their combined result intensifies side effects markedly and can be life-threatening.

Is Clonazepam Stronger Than Xanax?

Both drugs have a similar sedative effect. However, Klonopin has a longer half-life, meaning the drug effect lasts longer than Xanax and would theoretically need to be taken less often than Xanax. Half-life is affected by many factors and is an approximation only. Each person’s physiology is different.

For instance, Johns Hopkins Psychiatry Guide31 estimates the half-life of Klonopin at approximately 18 to 50 hours. The half-life of Xanax is roughly 12-15 hours, considerably shorter than Klonopin. They are both strong in their sedative effects, and both are susceptible to addiction or dependence.

Because they are both benzodiazepines, they should only be taken for a short time according to published guidelines on benzodiazepine use.

Clonazepam vs Xanax: What’s the Difference?

Both drugs belong to the benzodiazepine class, and are anxiolytic in their action. They are both used to treat anxiety and panic disorders, and both should be taken for the short term only as they are easy to get addicted to.

Because of differences in the half-life of these two drugs, Klonopin lasts much longer than Xanax, which is a shorter-acting medication.

Beyond other minor differences such as pricing, the effects of these two drugs are very similar to one another.

How Long Do Clonazepam Withdrawal Symptoms Last?

An individual who wishes to taper off clonazepam how long do symptoms lastKlonopin can expect the process to take some time and should be scheduled properly for a safe and gentle cessation experience. Many people choose inpatient care. Trying to keep working or going to school while at the same time trying to accomplish clonazepam withdrawal would be exhausting, and near-to-impossible. A much better approach is taking the time to focus on rest and recovery. Never abruptly stop taking Klonopin as prescribed, but seek medical guidance and oversight to gradually reduce the dosage over time.

In many studies, clonazepam withdrawal seems to occur in three stages of intensity. The first stage begins with the onset of withdrawals, which is generally considered to start over several days.

From around days 1 to 4, there can begin “rebound symptoms,” such as increased anxiety, worsened depression, or in the case of insomnia, the person can experience rebound insomnia and sleep interruptions, and other discomforts. This early period is called “acute withdrawal” and can be debilitating especially without support and proper care.

These symptoms can last for several weeks or a month or more, and will hopefully begin to subside after some time. This period is generally referred to as “post-acute withdrawal.”

Withdrawal symptomology can, however, last significantly longer, stretching out into many months and even years, especially without proper treatment, and this is called protracted withdrawal. During protracted withdrawal, patients report ongoing anxiety and other symptoms very similar to what would be expected during early withdrawal. There is some suspicion that this might be due to damaged receptors, or the ongoing effects of underlying neurotoxic poisoning. These patients are not generally understood well by the medical mainstream and are sometimes subjected to others doubting the validity of their symptoms, which tend to become further pathologized without proper treatment.12 It seems likely in many of these cases that mainstream medicine may need to catch up to real patient experience.1,7,16-20

Special Note Re: Pregnancy and Klonopin (clonazepam)

Women of child-bearing age, or who are planning a pregnancy should be informed of the risk of birth defects in infants whose mothers took Klonopin during pregnancy.4 Recommended would be a clonazepam withdrawal program before conceiving a child, even where pregnancy is not planned but possible.

Unique Factors in Clonazepam Withdrawal Programs

It is important to remember that each individual has uniqueness, including environmental, historical, genetic, and other differentiating factors that need to be addressed in any tapering program. No two people are the same, and the above is an estimated time-line that will apply to some but not apply to others.

Can You Overdose on Clonazepam (Klonopin)?

Yes. Klonopin is a powerful sedative and can be especially dangerous if too much is ingested, or if it is taken concurrently with alcohol, opiates, or any other medications that act as CNS depressants. Tragically, many opiate users also use Klonopin or other benzos concurrently. Approximately one-quarter of opioid overdose deaths also tested positive for benzodiazepines in their systems.5,25

Signs of clonazepam overdose14,27 include:

  • Unusual or extreme drowsiness
  • Confused or impaired cognitive abilities
  • Lack of coordination, loss of balance
  • Slowed reflexes
  • Slowed or stopped breathing
  • Loss of consciousness or coma
  • Can result in death

Treatment for Clonazepam (Klonopin) Abuse and Addiction

clonazepam withdrawal stabilize neurochemistryAt our holistic center, we strive to provide alternative treatments for anxiety or other unwanted conditions where drugs may have proven ineffective, or brought with them harsh side effects which outweighed any benefits.

One important facet of our clonazepam withdrawal program involves testing for and removing toxins that have accumulated over one’s lifetime in the body. Neurotoxicity is linked to many symptoms and our industrialized environment creates a continual assault on our health by exposure to poisons. The hundreds of thousands of various chemicals that our bodies are forced to deal with are certainly taking a toll on our hormones, neurochemistry, reproductive organs, and other innate physiology vital to our survival, as well as our mental health.28

Does Removal of Neurotoxins Aid in Clonazepam Withdrawal?

clonazepam withdrawal holistic treatmentLong-term success is supported by the extraction of excitotoxins. One example of a common excitotoxin is used in pesticides, such as organophosphates. This type of toxic accumulation can affect acetylcholinesterase enzymes, which in turn causes overstimulation of neuronal pathways.3,28

This can be helpful to understand during clonazepam withdrawal, and when addressing neurochemistry in general. Pesticides act on pests by knocking out the pest’s nervous system. There is a possible parallel in human physiology because we also have acetylcholine receptors. Because we have a liver to break down toxins, the impact may be somewhat different in humans than in a pest; however, an individual whose genetics have been compromised may have a similar liability linked to accumulated toxins. Pests react with twitching muscles and other unnatural body motions, not unlike those seen in humans with toxin-laden neurochemistry.

Effects of Food Additives on Neurochemistry

Even relatively common food additives such as MSG and aspartame have been linked to synaptic over-firing. These chemicals and their derivatives can stimulate receptors such as the NMDA receptor, resulting in neurotoxicity in these receptors.30  In contrast, after neurotoxicity is purged from the system, our clients typically report improvements in sleep, calmer mood, feeling brighter and more energetic, and other positive changes. But that is just the beginning. Authentic wellness is sustainable wellness.  Although the cumulative effects of many environmental toxins are as yet understudied, we do know that certain chemicals and toxic substances have specific detrimental effects on mental health, for example, the onset of Parkinson’s disease is associated with pesticide exposure.29

We cannot overstate the importance of neurotoxin removal for improvements in mental health. We have seen the results of this type of natural therapy on thousands of our clients.

Why Consider Inpatient Clonazepam Withdrawal?

Many medications such as clonazepam may give temporary relief of symptoms, but also bring with them intolerable side effects that lead to the decision to consider Klonopin withdrawal. One may find a more prudent approach is to look for other natural means to address mental health issues. Each person’s situation is highly specific to them and truly needs the guidance of an experienced and trusted medical team to determine the correct strategy. Alternative to Meds Center has developed a wealth of treatment strategies that not only help in reducing the discomfort of clonazepam withdrawal, but that are designed to give relief to one’s original symptoms, such as anxiety, insomnia, panic attacks, etc., without drugs. Please see our services overview page for a summary of many of the techniques and strategies used in our programs.

Clonazepam withdrawal and all it entails might be challenging to one’s family or home life. Many families have opted to seek inpatient care to take the stress off the situation and provide peace of mind for all concerned.

We can help in tapering from such medications comfortably and safely, and bridge over to alternative therapies that can bring relief of symptoms. Our aim is to help our clients attain natural sustainable mental health. Please ask us for more information on the extraordinarily effective clonazepam withdrawal programs we offer at Alternative to Meds Center, in beautiful Sedona Arizona.


1. FDA Label Clonazepam [Internet] 2017 Oct [cited 2021 May 31]

2. Torgeson T, “My Addiction to Benzos Was Harder to Overcome than Heroin.”  Healthline [Internet] N.D. [cited 2021 May 31]

3. Mattson MP, “Excitotoxins- an overview.” Science Direct [Internet] N.D. [cited 2021 May 31]

4. Almgren M, Kallen B, Lavebratt C, “Population-based study of antiepileptic drug exposure in utero — influence on head circumference in newborns.” US National Library of Medicine {Internet] 2009 Dec 18, 2009[cited 2021 May 31]

5. NIDA “Benzodiazepines and Opioids” [Internet] 2018 Mar 15[cited 2021 May 31]

6. “Drug Scheduling” U.S. Drug Enforcement Administration. [online] [cited 2021 May 31]

7. Pétursson H. The benzodiazepine withdrawal syndrome. Addiction. 1994 Nov;89(11):1455-9. doi: 10.1111/j.1360-0443.1994.tb03743.x. PMID: 7841856.[cited 2021 May 31]

8. Brett J, Murnion B. Management of benzodiazepine misuse and dependenceAust Prescr. 2015;38(5):152-155. doi:10.18773/austprescr.2015.055[cited 2021 May 31]

9. Lader M. Benzodiazepine harm: how can it be reduced? Br J Clin Pharmacol. 2014 Feb;77(2):295-301. doi: 10.1111/j.1365-2125.2012.04418.x. PMID: 22882333; PMCID: PMC4014015.[cited 2021 May 31]

10. Chouinard G. Issues in the clinical use of benzodiazepines: potency, withdrawal, and rebound. J Clin Psychiatry. 2004;65 Suppl 5:7-12. PMID: 15078112.[cited 2021 May 31]

11. Nelson J, Chouinard G. Guidelines for the clinical use of benzodiazepines: pharmacokinetics, dependency, rebound and withdrawal. Canadian Society for Clinical Pharmacology. Can J Clin Pharmacol. 1999 Summer;6(2):69-83. PMID: 10519733.[cited 2021 May 31]

12. Pimlott NJ, Hux JE, Wilson LM, Kahan M, Li C, Rosser WW. Educating physicians to reduce benzodiazepine use by elderly patients: a randomized controlled trial. CMAJ. 2003 Apr 1;168(7):835-9. PMID: 12668540; PMCID: PMC151988.[cited 2021 May 31]

13. FDA Drug Information: Benzodiazepines [online] Sept 23 2020 [cited 2021 May 31]

14. Statpearls authors Basit H, Kahwaji C, “Clonazepam” [online] April 29 2021 [cited 2021 May 31]

15. DEA Fact Sheet, “Benzodiazepines: Street Names” [online] December 2019 ]cited 2021 May 31]

16. Dept. Consumer Protection, “Clonazepam” fact sheet [online] N.D. [cited 2021 May 31]

17. Ashton H. Guidelines for the rational use of benzodiazepines. When and what to use. Drugs. 1994 Jul;48(1):25-40. doi: 10.2165/00003495-199448010-00004. PMID: 7525193. [cited 2021 May 31]

18. Lader M. Benzodiazepine harm: how can it be reduced? Br J Clin Pharmacol. 2014 Feb;77(2):295-301. doi: 10.1111/j.1365-2125.2012.04418.x. PMID: 22882333; PMCID: PMC4014015.[cited 2021 May 31]

19. Ashton, H, “The Ashton Manual” [online] [cited 2021 May 31]

20. Laskey C, Opitz B. Tinnitus associated with benzodiazepine withdrawal syndrome: A case report and literature reviewMent Health Clin. 2020;10(3):100-103. Published 2020 May 7. doi:10.9740/mhc.2020.05.100 [cited 2021 May 31]

21. Bounds CG, Nelson VL. Benzodiazepines. [Updated 2020 Nov 22]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470159/ [cited 2021 May 31]

22. Tapiainen V, Taipale H, Tanskanen A, Tiihonen J, Hartikainen S, Tolppanen AM. The risk of Alzheimer’s disease associated with benzodiazepines and related drugs: a nested case-control study. Acta Psychiatr Scand. 2018 Aug;138(2):91-100. doi: 10.1111/acps.12909. Epub 2018 May 31. PMID: 29851063. [cited 2021 May 31]

23. Rajamaki B, Hartikainen S, Tolppanen AM. Psychotropic Drug-Associated Pneumonia in Older Adults. Drugs Aging. 2020 Apr;37(4):241-261. doi: 10.1007/s40266-020-00754-1. PMID: 32107741; PMCID: PMC7096389. [cited 2021 May 31]

24. Haefely W. Benzodiazepine interactions with GABA receptors. Neurosci Lett. 1984 Jun 29;47(3):201-6. doi: 10.1016/0304-3940(84)90514-7. PMID: 6147796. [cited 2021 May 31]

25. Petit J, Sansone RA. A case of interdose discontinuation symptoms with venlafaxine extended release. Prim Care Companion CNS Disord. 2011;13(5):PCC.11l01140. doi:10.4088/PCC.11l01140 [cited 2021 May 31]

26. NIH, “Benzodiazepines and Opioids” [online] [cited 2021 May 31]

27. Welch TR, Rumack BH, Hammond K. Clonazepam overdose resulting in cyclic coma. Clin Toxicol. 1977;10(4):433-6. doi: 10.3109/15563657709046280. PMID: 862377. [2021 May 31]

28. Brown JS Jr. Psychiatric issues in toxic exposures. Psychiatr Clin North Am. 2007 Dec;30(4):837-54. doi: 10.1016/j.psc.2007.07.004. PMID: 17938048. [cited 2021 May 31]

29. Costa LG, Giordano G, Guizzetti M, Vitalone A. Neurotoxicity of pesticides: a brief review. Front Biosci. 2008 Jan 1;13:1240-9. doi: 10.2741/2758. PMID: 17981626. [cited 2021 May 31]

30. Choudhary AK, Lee YY. Neurophysiological symptoms and aspartame: What is the connection? Nutr Neurosci. 2018 Jun;21(5):306-316. doi: 10.1080/1028415X.2017.1288340. Epub 2017 Feb 15. PMID: 28198207. [cited 2021 May 31]

31. Johns Hopkins “Psychiatry Guide, Benzodiazepines” [online] [cited 2021 May 31]


Originally Published Sep 13, 2018 by Diane Ridaeus


This content has been reviewed and approved by a licensed physician.

Dr. Michael Loes, M.D.

 

Dr. Michael Loes is board-certified in Internal Medicine, Pain Management and Addiction Medicine. He holds a dual license in Homeopathic and Integrative Medicine. He obtained his medical doctorate at the University of Minnesota, Minneapolis, MN, 1978. Dr. Loes performed an externship at the National Institute of Health for Psychopharmacology. Additionally, he is a well-published author including Arthritis: The Doctor’s Cure, The Aspirin Alternative, The Healing Response, and Spirit Driven Health: The Psalmist’s Guide for Recovery. He has been awarded the Minnesota Medical Foundation’s “Excellence in Research” Award.

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Clonazepam Withdrawal Symptoms | Klonopin Side Effects, Treatment Help
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