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Risperdal Alternatives

This entry was posted in Antipsychotic and tagged on by .
Medically Reviewed Fact Checked

Last Updated on July 1, 2022 by Carol Gillette

Alternative to Meds Editorial Team
Medically Reviewed by Dr Samuel Lee MD

Anyone considering Risperdal alternatives probably is already aware this drug is one of the more potent antipsychotic drugs on the market. In order to convert from the medication to Risperdal alternatives, it is highly recommended to seek professional guidance.

At Alternative to Meds Center, we understand the risks posed by this drug and we serve as guides for those who are considering the transition. We’ve been there. We know what it takes.

Do Your Symptoms
Require Risperdal?

successful alternatives to risperdal
Alternative to Meds has been the expert on antipsychotic alternatives for over 15 years. We have published evidence regarding our clients’ success within the structured programs offered at Alternative to Meds. Whether there were underlying issues or medical conditions that were overlooked, or other factors that led to being prescribed antipsychotic medications, we have helped clients find authentic relief through non-toxic treatments without the fear and anxiety that an inaccurate diagnosis can cause.
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Why Choose Alternatives to Risperdal?

Risperdal® can cause some severe side effects that may make it difficult to continue taking the drug. And some may not feel the drug has helped them as was hoped. Certain age groups should be made aware of potentially severe reactions according to FDA guidelines.1,3,15 Common adverse reactions to Risperdal include tremors, and hyperprolactinemia which can lead to cessation of menstruation, infertility, sexual dysfunction, and development of breast milk in both sexes.65& Aside from those unpleasant side effects. antipsychotics may also cause a person to feel disconnected from life, making it difficult to set goals and function in life as they would like to. These are some familiar reasons we have often heard from clients who opted for exploring alternatives to Risperdal.2

Did you know that In some clinical trials, potential candidates are excluded from the trial if they have an initial bad reaction to the drug? The results of such a trial may, therefore, be only partially accurate.5 In any case, there are many Risperdal alternatives including other lesser medications, psychotherapy, and natural holistic therapies that are much safer.

Risperdal has been licensed for treating schizophrenia in adults and teens, (but not children), and for manic and depressive (or mixed) episodes of bipolar disorder from age 10 and up. For autistic children, it can be prescribed to children as young as 5 years old. The drug is proven to cause breast growth as well as lactation in male children and adults, for which the drugmaker was sued in 2018. Johnson & Johnson was additionally sued for illegally marketing Risperdal off-label and the drugmaker has paid billions of dollars in fines. Risperdal lawsuits were filed against the drugmaker because these and other serious side effects were discovered to be hidden from the public.7,15

Natural Alternatives to Risperdal

If bothersome side effects arise while taking Risperdal or if this medication is not effective at treating your condition, there are natural Risperdal alternatives. Even if this drug does manage symptoms to a degree and side effects are not that severe, one may find Risperdal (risperidone) alternatives can help a person regain the full level of health and quality of life that is desired.

Natural Alternatives to Risperdal Include:
  • holistic therapies as risperdal alternativesCBT and other genres of psychological therapy. 16
  • Modified diet, plenty of fresh fruits and vegetables, avoid gluten 6,9,20
  • Test for food allergies 8,9,10
  • Gut microbiome support 17,18,19
  • Avoid foods processed with chemicals, pesticides, artificial coloring/flavoring agents, MSG, or other additives 21,64
  • Cut sugars and refined carbs, take 4-6 small meals and adequate protein to keep blood sugar levels in check over the day 22,23
  • Avoid foods and beverages high in caffeine or other stimulants 24
  • Get tested for nutritional deficiencies and correct them 25
  • Supplements such as tryptophan 26 omega 3 fatty acids, and EPA 27,28,29
  • Lithium Orotate 31-39,59
  • Orthomolecular use of Niacin and Vitamin C 40,41
  • Avoid neurotoxin exposures and clean out toxic accumulations from the body 11-14,42,43
  • Adequate exposure to sunlight and regular exercise 44,45
  • Improve sleep with non-drug-based treatments including CBT, optimizing sleeping quarters with good ventilation, light and sound reduction, eliminating nocturnal electronics and blue-light 46,62.63
  • Eliminate alcohol, cannabis, and other recreational substance use/abuse 47-49

Talk Therapy as an Alternative to Risperdal

open dialogue talk therapyMorrison’s 2009 study on CBT in the treatment of schizophrenia found that the core symptoms of schizophrenia are often resistant to medication-based treatment, but can significantly improve with cognitive behavioral therapy. Benefits to family and other relationships, as well as improvements in the workplace, are noted, along with an expressed call for more research on this under-studied area of human health.50

Another type of non-drug-based therapy is found in the Open Dialogue approach in the treatment of schizophrenia and other disorders. Psychological treatment combined with peer support and family support in a residential setting has shown to be a highly effective natural alternative to Risperdal and similar medications.

Open Dialogue began in Finland and its concepts are now in use in European countries and the US. OD has documented a reduction in symptoms of psychosis, fewer hospitalizations, a reduction in the use of medications, and improved employment rates leading to improved quality of life for participants in the program.51

Talk therapy includes many formats, such as:

  • Cognitive Behavioral Therapy CBT 16
  • ODT or Open Dialogue Therapy 51
  • EMDR (eye-movement desensitization & reprocessing therapy) 52
  • Exposure-based CBT therapy 53

CBT and Exposure Therapy as Risperdal Alternatives

Risperdal alternatives can utilize a blend of many different therapies. CBT (cognitive behavioral therapy) also has various formats to address specific populations that could benefit. For instance, exposure-based therapy is one form of psychotherapy that is reported to be particularly beneficial to trauma and PTSD-related symptoms.

Counseling can provide the safe space needed to gradually overcome subjects of anxiety or other unwanted feelings. Psychotherapy can be done in a group or individual session format.

Diet Correction as a Risperdal Alternative

diet correction as risperdal alternativeIt is traditional for physicians to recommend beneficial modifications to diet, restricting sugars, and gluten, and making other changes.

Persons with symptoms of schizophrenia, psychosis, bipolar episodes, and other conditions have seen a tangible improvement in their well-being, energy level, mood, and many other benefits with better dietary choices.17,18,19,30

Changing the diet has been shown extremely effective in reducing or eliminating symptoms associated with schizophrenia and other psychiatric conditions.6,9,20

Addressing Food Allergies, Nutrients, as a Natural Risperdal Substitute

Food allergies can prompt the response of psychiatric symptoms. After testing for food allergies or other sources of sensitivity, strategic food choices can avoid such reactions.

Numerous studies have reported that specific nutrients including vitamins B12, B6, folate, amino acids, zinc, and amino acids such as serine, lysine, glycine, and tryptophan play a role in supporting a healthy and functioning microbiome that is essential to good health.30,31,34

The monitoring and control of gluten sensitivity may have significant effects on the management of individuals hospitalized with acute mania, and studies suggest a link between symptoms of celiac disease and schizophrenia that may be mitigated by a diet that omits foods high in gluten such as wheat and other flours, starches, etc.9,10

The Microbiome and Psychosis-Bipolar Presentations

microbiome bipolar connectionThe microbiome is defined as all the microorganisms in the human body and their respective genetic material. Microbiota is the term used when focusing on a particular part of the body and the microorganisms found there. The condition of the microbiota of the gut is of particular interest in mental health. This connection is termed “the gut-brain axis.” The relationship between the gut and the brain develops from infancy and continues to develop throughout one’s life, involving hormones, bacteria, emotional responses, digestion, energy, organ function, and more. According to a review of clinical data, Nguyen et al suggest there are differences in the microbiota of the gut comparing schizophrenic patients and non-schizophrenic controls.18

A study by Severance et al on the microbiome’s effects on mental health showed that inflammation in the digestive tract can cause bacteria to become released systemically which can impact synapse activity in the brain. This research does not definitively conclude a link between schizophrenia and pathological disruption in the gut, but certainly suggests the likelihood of a connection between a properly functioning microbiome and good health.19

Clapp et al’s 2017 study on gut microbiota and mental health suggests that the use of probiotics can restore normal microorganisms which may assist in the treatment and even the prevention of psychiatric symptoms.54

Research by Bonaz et al on the gut-brain axis and how it can affect the vagus nerve highlights the positive effects upon the CNS that are to be gained from restoring microbiota balance.60

MSG and Glutamate containing foods

MSG, or monosodium glutamate, is synthesized when one sodium molecule is added to glutamate or L-glutamic acid. L-Glutamic acid is the most prevalent amino acid in the body and performs innumerable vital roles in a healthy body. Synthesized MSG is widely used as a flavor enhancer in processed foods. While the FDA and the World Health Organization have never openly stated that MSG is an excitotoxin that can affect some with neuronal sensitivities, (as has been shown to be the case in baby rat studies) the safety study by the FDA does not rule out potential harm that MSG could do in persons with neuronal sensitivities.55

Maintain Blood Sugar Levels Through Diet

The brain needs a steady supply of certain fuels to operate properly. Glucose (blood sugar) is one of the brain’s preferred types of fuel. Diet is an effective tool to maintain sufficient glucose to ensure optimal CNS operation.22,23

Eliminate Caffeine

Heavy intake of caffeine has been shown to impact (over-stimulate) neurochemistry. This can be quite unwise in people with sensitivities to such stimulants. Caffeine can be a powerful neuro-stimulant. In one compelling case study, eliminating caffeine was followed by an immediate remission of psychiatric symptoms that 10 years of medications did not resolve.24

Supplements Used as Risperdal Alternatives


ADT or acute tryptophan depletion was found in clinical observations to be linked with aggression, low mood, and suicidality in some persons. Studies suggest that tryptophan may be lacking in persons with schizophrenic presentations and can be corrected with supplementation as well as diet.26,56,57,58

Lithium Orotate

Lithium orotate is the trace mineral form of lithium. Positive results have been documented without the toxic side effects that can occur with pharmaceutical lithium carbonate, showing a reduction of manic and depressive symptoms in bipolar patients.59

Orthomolecular Use of High-Dose Niacin and Vitamin C

Dr. Abram Hoffer’s work in the 1950s forward demonstrated much success in the treatment of schizophrenia using various forms of niacin (vitamin B3) and vitamin C. His work showed a high remission rate and forged a strong pathway forward for what is now called Orthomolecular Medicine.

Alternative to Meds Center is a proponent of these and other orthomolecular treatments for our patients. The center attributes much of our clients’ success to these principles.40,41

Omega-3 Fatty Acids and Eicosapentaenoic Acid (EPA)

Omega-3 fatty acids have become widely studied as an alternative to Risperdal and other antipsychotic medications. Studies show a positive correlation between high-fat consumption, particularly omega-3 fatty acids, and better treatment outcomes for schizophrenia patients. EPA or eicosapentaenoic acid is one of the components of omega-3 fish oils and has been successfully used in the treatment of psychiatric symptoms and schizophrenia.28,29

Test for and Cleanse Toxic Accumulations

cleanse toxic accumulationA host of neurotoxins have been identified as endocrine disruptors and possible contributors to psychiatric symptoms. The chemicals used in dry cleaning, industrial or home-use cleaners, dental or other mercury exposures, and many other sources can be tested for and cleansed from the body, to promote neurochemistry to re-normalize naturally.11,12,13,14

Most of us can recall hearing the idiom “mad as a hatter” in movies and stories, without realizing where that phrase derived from. In the 18th and 19th centuries, compounds that were used in making felt hats gave off poisonous mercury vapors, causing psychiatric symptoms in the hat makers, or “hatters.” Symptoms of mercury poisoning can be severe and disabling.

Animal studies demonstrate that mercury influences the reuptake of glutamate, leading to neurotoxicity. Similar abnormalities in glutamate transmission occur in persons with schizophrenia, a neurological disorder that shares certain common features in autistic persons. Where psychiatric symptoms arise after exposure to toxins, an alternative to Risperdal is to cleanse these out of the system for relief.13

Exercise, Especially Cardio, Yoga, Walking

Mittal et al’s fascinating clinical research published in the Journal of Current Treatment Options in Psychiatry investigated results of cardio, aerobic, and other regular, moderately intense exercise on mental health. Their research suggests that there is a link between this type of activity and regeneration of healthy neurochemistry and improved cognitive abilities in persons with psychiatric disorders such as psychosis and schizophrenia. This is astounding information! Exercise is a proven but underutilized alternative to pharmacological treatments.44

Get Adequate Sleep

As Seibum et al’s research published in Neurotherapeutics shows insomnia is often seen concurrently with other physical and mental health issues. There can be various causes for insomnia and sleep disturbances, but without proper sleep, anyone’s daytime functioning can be impaired and put under undue strain. CBT, relaxation exercises, and other non-drug-based alternatives to Risperdal may be able to help resolve this potentially ruinous symptom.46

Eliminate Cannabis Use

Cannabis use has skyrocketed in North America, having moved from an illicit to a legalized drug in recent years in many locales. Cannabis-induced psychosis is a matter of concern more than ever, according to a study by Grewal et al recently published in the Psychiatric Times. Many earlier studies have likewise demonstrated this tragic phenomenon. In one case highlighted in the Grewal et al study, a young girl who had been smoking marijuana since the age of 17 developed symptoms such as paranoia and unreality while in college. This is a not uncommon occurrence in marijuana users, that researchers attribute to the THC content.61 She attributed her anxieties and perceived adversaries to the competitiveness of the environment and not to her drug use. Through CBT (counseling) and other non-pharmacological treatments, she was able to re-set this pattern and decided to abstain from marijuana, and a year later she was able to return to college symptom-free.47,48,49

Natural Risperdal Alternatives vs Medication-Based Treatment

There is no cookie-cutter answer to mental health concerns. It takes being interested enough to look for contributing factors, to spot overlooked medical or genetic factors, and to assess what lifestyle factors can be better managed, including diet, sleep, exercise, and others. Quality research is more prevalent than ever before, and we find that natural alternatives can be highly effective for natural mental health, and sometimes more so in comparison to the limits of managing (suppressing) symptoms with heavy drugs.

Risperdal, an atypical antipsychotic, also known as a second-generation antipsychotic, is licensed to treat schizophrenia, bipolar disorder, and irritability related to autism in children. Individuals are often put on an antipsychotic after a psychotic break, or after other medications have been tried and have been ineffective. This antipsychotic and others of its kind may seem effective and tolerable on the onset however, these drugs are usually not well tolerated for prolonged use. In fact, lawsuits have arisen from injuries such as movement disorders, attributed to drugs like Risperdal.1,2,7

How Alternative to Meds Center Gets Its Successful Results

The traditional and most commonly suggested Risperdal alternatives are other medications and therapy. Risperdal is often already being used as an alternative to other previously ineffective antipsychotics or antidepressants. When individuals are having problems with this medication, it may be time to consider alternatives that do not include the burdens of prescription medications. Fortunately, there are many ways to control mental health symptoms and disorders without the use of psychiatric medications. Using another medication as an alternative to this drug is likely to cause many of the same problems that were experienced with Risperdal. Medications that are prescribed by traditional medical professionals as alternatives to Risperdal include other atypical antipsychotics such as clozapine or Clozaril, and typical (first-generation) antipsychotics such as haloperidol or Haldol.

Drug-free therapy can include many possible Risperdal alternative treatments that could be effective in treating symptoms that these drugs attempt to manage. It is unfortunate that in Western countries especially, nonpharmacological interventions are quite rarely administered in favor of drug therapy.4 As discussed above, psychosocial support and psychotherapy (talk therapy) have been found to be very helpful in offering guidance, and constructive education to individuals with mental disorders, as well as their families.

Alternative to Meds Center uses lab tests to identify underlying causes for the original symptoms, where toxicity is an often-found culprit.

antipsychotic natural alternativesOur program includes medical professionals to aid individuals in reducing dependence upon Risperdal. This is done by utilizing carefully planned tapering techniques, using natural substances to stabilize the neurochemistry, and removing neurotoxins that may have contributed to original symptoms that lead to being medicated with an antipsychotic. We also provide counseling services, nebulized glutathione treatments, correction and enhancement of diet, environmental medicine, personal exercise training, Qi Gong, peer support, massage, yoga, targeted nutritional therapy, acupuncture, and many other effective Risperdal natural alternatives to address the expected withdrawal symptoms and side effects. Sugar, processed food, cigarettes, and caffeine are restricted and supplements that are beneficial to these individuals are used. Once the individual is stable and sedated, Risperdal can be slowly reduced and the dosage can be adjusted if needed.

There is much more to learn about the underlying reasons why antipsychotic medications could have been prescribed. Please call us for more information about the effective methods of natural Risperdal alternatives that help our clients to regain a more satisfying quality of life.

1. Alladi, Charanraj Goud et al. “Risperidone-Induced Adverse Drug Reactions and Role of DRD2 (-141 C Ins/Del) and 5HTR2C (-759 C>T) Genetic Polymorphisms in Patients with Schizophrenia.” Journal of pharmacology & pharmacotherapeutics vol. 8,1 (2017): 28-32. doi:10.4103/jpp.JPP_197_16 [cited 2022 June 24]

2. Matthews Maju, Gratz S, Adetunji B, George V, Matthews Manu, Biju B “Antipsychotic-Induced Movement Disorders – Evaluation and Treatment.” Psychiatry MMC Journal [Internet] 2005 Mar  [cited 2022 June 22]

3. Lee PE, Sykora K, Gill SS, Mamdani M, Marras C, Anderson G, Shulman KI, Stukel T, Normand SL, Rochon PA. Antipsychotic medications and drug-induced movement disorders other than parkinsonism: a population-based cohort study in older adults. J Am Geriatr Soc. 2005 Aug;53(8):1374-9. doi: 10.1111/j.1532-5415.2005.53418.x. PMID: 16078964. [cited 2022 June 24]

4. Stevović LI, Repišti S, Radojičić T, Sartorius N, Tomori S, Džubur Kulenović A, Popova A, Kuzman MR, Vlachos II, Statovci S, Bandati A, Novotni A, Bajraktarov S, Panfil AL, Maric NP, Delić M, Jovanović N. Non-pharmacological treatments for schizophrenia in Southeast Europe: An expert survey. Int J Soc Psychiatry. 2021 Aug 14:207640211023072. doi: 10.1177/00207640211023072. Epub ahead of print. PMID: 34392727. [cited 2022 June 24]

5. Fogel DB. Factors associated with clinical trials that fail and opportunities for improving the likelihood of success: A review. Contemp Clin Trials Commun. 2018;11:156-164. Published 2018 Aug 7. doi:10.1016/j.conctc.2018.08.001 [cited 2022 June 24]

6. Aucoin M, LaChance L, Clouthier SN, Cooley K. Dietary modification in the treatment of schizophrenia spectrum disorders: A systematic review. World J Psychiatry. 2020 Aug 19;10(8):187-201. doi: 10.5498/wjp.v10.i8.187. PMID: 32874956; PMCID: PMC7439299. [cited 2022 June 22]

7. McCarthy M, Companies to pay $39.5m in OxyContin and Risperdal cases. BMJ 2015;351:h7018 [cited 2022 June 24]

8. Aucoin M, LaChance L, Cooley K, Kidd S. Diet and Psychosis: A Scoping Review. Neuropsychobiology. 2020;79(1):20-42. doi: 10.1159/000493399. Epub 2018 Oct 25. PMID: 30359969.[cited 2022 June 22]

9. Dickerson F, Stallings C, Origoni A, Vaughan C, Khushalani S, Yolken R. Markers of gluten sensitivity in acute mania: a longitudinal study. Psychiatry Res. 2012 Mar 30;196(1):68-71. doi: 10.1016/j.psychres.2011.11.007. Epub 2012 Mar 3. PMID: 22386570. [cited 2022 June 22]

10. Samaroo D, Dickerson F, Kasarda DD, et al. Novel immune response to gluten in individuals with schizophrenia.Schizophr Res. 2010;118(1-3):248-255. doi:10.1016/j.schres.2009.08.009 [cited 2022 June 22]

11. Arinola G, Idonije B, Akinlade K, Ihenyen O. Essential trace metals and heavy metals in newly diagnosed schizophrenic patients and those on anti-psychotic medication. J Res Med Sci. 2010;15(5):245-249.[cited 2022 June 22]

12. MAGHAZAJI H I, Psychiatric aspects of methylmercury poisoning  Journal of Neurology, Neurosurgery, and Psychiatry, 1974, 37, 954-958 From the Department of Medicine, Medical College, Baghdad University [cited 2022 June 24]

13. Aschner, M., Walker, S. The neuropathogenesis of mercury toxicity. Mol Psychiatry 7, S40–S41 (2002). [cited 2022 June 24]

14. Xuebing Huang, Samuel Law, Dan Li,  Xin Yu, Bing Li, Mercury Poisoning: A Case of a Complex Neuropsychiatric Illness The American Journal of Psychiatry [cited 2022 June 24]

15. FDA label Risperdal (risperidone) approval 1993 Revised June 2009 [cited 2022 June 22]

16. David D, Cristea I, Hofmann SG. Why Cognitive Behavioral Therapy Is the Current Gold Standard of Psychotherapy. Front Psychiatry. 2018;9:4. Published 2018 Jan 29. doi:10.3389/fpsyt.2018.00004 [cited 2022 June 22]

17. Kraeuter AK, Phillips R, Sarnyai Z. The Gut Microbiome in Psychosis From Mice to Men: A Systematic Review of Preclinical and Clinical Studies. Front Psychiatry. 2020;11:799. Published 2020 Aug 11. doi:10.3389/fpsyt.2020.00799 [cited 2022 June 22]

18. Nguyen T T, Hathaway H, Kosciolek T, Knight R, Jeste D V, Gut microbiome in serious mental illnesses: A systematic review and critical evaluation, Schizophrenia Research, 2019, Aug 26, ISSN 0920-9964 [cited 2022 June 24]

19. Emily G. Severance, Robert H. Yolken, William W. Eaton, Autoimmune diseases, gastrointestinal disorders and the microbiome in schizophrenia: more than a gut feeling, Schizophrenia Research, Volume 176, Issue 1, 2016, Pages 23-35, ISSN 0920-9964, [cited 2022 June 22]

20. Levinta A, Mukovozov I, Tsoutsoulas C. Use of a Gluten-Free Diet in Schizophrenia: A Systematic Review. Adv Nutr. 2018;9(6):824-832. doi:10.1093/advances/nmy056 [cited 2022 June 24]

21. Khalil RM, Khedr NF. Curcumin Protects against Monosodium Glutamate Neurotoxicity and Decreasing NMDA2B and mGluR5 Expression in Rat Hippocampus. Neurosignals. 2016;24(1):81-87. doi: 10.1159/000442614. Epub 2016 Aug 17. PMID: 27529496. [cited 2022 June 22]

22. Padder T, et al,  Acute Hypoglycemia Presenting as Acute Psychosis Published December 2005 Priory Lodge Education [cited 2022 June 22]

23. Brady WJ Jr, Duncan CW. Hypoglycemia masquerading as acute psychosis and acute cocaine intoxication. Am J Emerg Med. 1999 May;17(3):318-9. doi: 10.1016/s0735-6757(99)90140-7. PMID: 10337905. [cited 2022 June 22]

24. Leonardo Tondo, Nereide Rudas, The course of a seasonal bipolar disorder influenced by caffeine, Journal of Affective Disorders, Volume 22, Issue 4, 1991, Pages 249-251. [cited 2022 June 22]

25. Understanding nutrition, depression and mental illnesses Indian J Psychiatry. 2008 Apr-Jun; 50(2): 77–82. T. S. Sathyanarayana Rao, M. R. Asha, B. N. Ramesh, and K. S. Jagannatha Rao [cited 2022 June 22]

26. van der Heijden, F., Fekkes, D., Tuinier, S. et al. Amino acids in schizophrenia: evidence for lower tryptophan availability during treatment with atypical antipsychotics?. J Neural Transm 112, 577–585 (2005). [cited 2022 June 22]

27. Christensen O, Christensen E, Fat consumption and schizophrenia Acta Psychiatrica Scandinavica November 1988. [cited 2022 June 24]

28. McNamara R K, “Mitigation of Inflammation-Induced Mood Dysregulation by Long-Chain Omega-3 Fatty Acids.” Journal of American College of Nutrition [Internet] 2015;34 Suppl 1(0 1):48-55. DOI: 10.1080/07315724.2015.1080527 [cited 2022 June 22]

29. Malcolm Peet, Eicosapentaenoic acid in the treatment of schizophrenia and depression: rationale and preliminary double-blind clinical trial results, Prostaglandins, Leukotrienes and Essential Fatty Acids, Science Direct, Volume 69, Issue 6, 2003, Pages 477-485. [cited 2022 June 24]

30. Gurusamy J, Gandhi S, Damodharan D, Ganesan V, Palaniappan M. Exercise, diet and educational interventions for metabolic syndrome in persons with schizophrenia: A systematic review. Asian J Psychiatr. 2018 Aug;36:73-85. doi: 10.1016/j.ajp.2018.06.018. Epub 2018 Jun 30. PMID: 29990631. [cited 2022 June 22]

31. National Research Council (US) Committee on Diet and Health. Diet and Health: Implications for Reducing Chronic Disease Risk. Washington (DC): National Academies Press (US); 1989. 14, Trace Elements. [cited 2022 June 22]

32. Cain L, LOW-DOSE LITHIUM: AN EFFECTIVE TREATMENT FOR MOOD DISORDERS Naturopathic Doctor News and Review Published online 2020 Mar 2 [cited 2022 June 24]

33. H.E. Sartori, Lithium orotate in the treatment of alcoholism and related conditions, Alcohol, Volume 3, Issue 2, 1986, Pages 97-100, ISSN 0741-8329. [cited 2022 June 22]

34. Aucoin M, LaChance L, Clouthier SN, Cooley K. Dietary modification in the treatment of schizophrenia spectrum disorders: A systematic review. World J Psychiatry. 2020 Aug 19;10(8):187-201. doi: 10.5498/wjp.v10.i8.187. PMID: 32874956; PMCID: PMC7439299. [cited 2022 June 22]

35. Pacholko AG, Bekar LK. Lithium orotate: A superior option for lithium therapy? Brain Behav. 2021 Jul 1. doi: 10.1002/brb3.2262. Epub ahead of print. PMID: 34196467. [cited 2022 June 22]

36. Kling MA, Manowitz P, Pollack IW. Rat brain and serum lithium concentrations after acute injections of lithium carbonate and orotate. J Pharm Pharmacol. 1978 Jun;30(6):368-70. doi: 10.1111/j.2042-7158.1978.tb13258.x. PMID: 26768. [cited 2022 June 22]

37. Sher L. Suicide in men. J Clin Psychiatry. 2015 Mar;76(3):e371-2. doi: 10.4088/JCP.14com09554. PMID: 25830461. [cited 2022 June 24]

38. Schrauzer, G.N., Shrestha, K.P. Lithium in drinking water and the incidences of crimes, suicides, and arrests related to drug addictions. Biol Trace Elem Res 25, 105–113 (1990). [cited 2022 June 22]

39. Cipriani A, Hawton K, Stockton S, Geddes J R Lithium in the prevention of suicide in mood disorders: updated systematic review and meta-analysis BMJ 2013; 346 (Published 27 June 2013) [cited 2022 June 24]

40. Hoffer A, Osmond H. TREATMENT OF SCHIZOPHRENIA WITH NICOTINIC ACID. A TEN YEAR FOLLOW-UP. Acta Psychiatr Scand. 1964;40(2):171-89. doi: 10.1111/j.1600-0447.1964.tb05744.x. PMID: 14235254. [cited 2022 June 22]

41. Hoffer A, Orthomolecular Treatment of Schizophrenia [September 28-30, 1971] [cited 2022 June 22]

42. Environmental Exposures and Depression: Biological Mechanisms and Epidemiological Evidence Annual Review of Public Health Vol. 40:239-259 (Volume publication date April 2019) First published as a Review in Advance on 2019 Jan 11 [cited 2022 June 22]

43. Collaborative on Mental Health and the Environment Mental Health and Environmental Exposures from the Learning and Developmental Disabilities Initiative, November 2008. [cited 2022 June 22]

44. Mittal VA, Vargas T, Osborne KJ, et al. Exercise Treatments for Psychosis: A Review. Curr Treat Options Psychiatry. 2017;4(2):152-166. doi:10.1007/s40501-017-0112-2. [cited 2022 June 22]

45. Mead MN. Benefits of sunlight: a bright spot for human health [published correction appears in Environ Health Perspect. 2008 May;116(5):A197]. Environ Health Perspect. 2008;116(4):A160-A167. doi:10.1289/ehp.116-a160 [cited 2022 June 22]

46. Siebern AT, Suh S, Nowakowski S. Non-pharmacological treatment of insomnia. Neurotherapeutics. 2012;9(4):717-727. doi:10.1007/s13311-012-0142-9 [cited 2022 June 22]

47. Grewal R S, George T P, Cannabis-Induced Psychosis: A Review Psychiatric Times, Vol 34 No 7, Volume 34, Issue 7July 14, 2017 [cited 2022 June 24]

48. Arendt M, Rosenberg R, Foldager L, Perto G, Munk-Jørgensen P. Cannabis-induced psychosis and subsequent schizophrenia-spectrum disorders: follow-up study of 535 incident cases. Br J Psychiatry. 2005 Dec;187:510-5. doi: 10.1192/bjp.187.6.510. PMID: 16319402. [cited 2022 June 22]

49. Rottanburg D, Robins A H, Ben-Arie O, Teggin A, Elk R. Cannabis-associated psychosis with hypomanic features Lancet. 1982 Dec 18;2(8312):1364-6. doi: 10.1016/s0140-6736(82)91270-3. PMID: 6129463. [cited 2022 June 22]

50. Morrison AK. Cognitive behavior therapy for people with schizophrenia. Psychiatry (Edgmont). 2009;6(12):32-39. [cited 2022 June 22]

51. Freeman et al., “Open Dialogue: A Review of the Evidence.” published in Psychiatryonline 18 Oct 2018 [cited 2022 June 22]

52. Wilson G, Farrell D, Barron I, Hutchins J, Whybrow D, Kiernan MD. The Use of Eye-Movement Desensitization Reprocessing (EMDR) Therapy in Treating Post-traumatic Stress Disorder-A Systematic Narrative Review. Front Psychol. 2018;9:923. Published 2018 Jun 6. doi:10.3389/fpsyg.2018.00923 [cited 2022 June 22]

53. Frueh BC, Grubaugh AL, Cusack KJ, Kimble MO, Elhai JD, Knapp RG. Exposure-based cognitive-behavioral treatment of PTSD in adults with schizophrenia or schizoaffective disorder: a pilot study. J Anxiety Disord. 2009;23(5):665-675. doi:10.1016/j.janxdis.2009.02.005 [cited 2022 June 22]

54. Clapp M, Aurora N, Herrera L, Bhatia M, Wilen E, Wakefield S. Gut microbiota’s effect on mental health: The gut-brain axis. Clin Pract. 2017;7(4):987. Published 2017 Sep 15. doi:10.4081/cp.2017.987 [cited 2022 June 22]

55. Walker R, Lupien J R, The Safety Evaluation of Monosodium Glutamate, The Journal of Nutrition, Volume 130, Issue 4, April 2000, Pages 1049S–1052S [cited 2022 June 22]

56. Young S N. The effect of raising and lowering tryptophan levels on human mood and social behaviour. Philos Trans R Soc Lond B Biol Sci. 2013;368(1615):20110375. Published 2013 Feb 25. doi:10.1098/rstb.2011.0375 [cited 2022 June 22]

57. Lakhan S E, Vieira KF. Nutritional therapies for mental disorders. Nutr J. 2008;7:2. Published 2008 Jan 21. doi:10.1186/1475-2891-7-2 [cited 2022 June 22]

58. van der Heijden, F., Fekkes, D., Tuinier, S. et al. Amino acids in schizophrenia: evidence for lower tryptophan availability during treatment with atypical antipsychotics?. J Neural Transm 112, 577–585 (2005). [cited 2022 June 22]

59. Zemlan FP, Hirschowitz J, Sautter FJ, Garver DL. Impact of lithium therapy on core psychotic symptoms of schizophrenia. Br J Psychiatry. 1984 Jan;144:64-9. doi: 10.1192/bjp.144.1.64. PMID: 6419805. [cited 2022 June 24]

60. Bonaz B, Bazin T, Pellissier S. The Vagus Nerve at the Interface of the Microbiota-Gut-Brain Axis. Front Neurosci. 2018 Feb 7;12:49. doi: 10.3389/fnins.2018.00049. PMID: 29467611; PMCID: PMC5808284. [cited 2022 June 22]

61. Deiana S. Medical use of cannabis. Cannabidiol: a new light for schizophrenia? Drug Test Anal. 2013 Jan;5(1):46-51. doi: 10.1002/dta.1425. Epub 2012 Oct 25. PMID: 23109356. [cited 2022 June 22]

62. Batalla-Martín D, Belzunegui-Eraso A, Miralles Garijo E, Martínez Martín E, Romaní Garcia R, Heras JSM, Lopez-Ruiz M, Martorell-Poveda MA. Insomnia in Schizophrenia Patients: Prevalence and Quality of Life. Int J Environ Res Public Health. 2020 Feb 19;17(4):1350. doi: 10.3390/ijerph17041350. PMID: 32093111; PMCID: PMC7068578. [cited 2022 June 22]

63. Shechter A, Kim EW, St-Onge MP, Westwood AJ. Blocking nocturnal blue light for insomnia: A randomized controlled trial. J Psychiatr Res. 2018;96:196-202. doi:10.1016/j.jpsychires.2017.10.015 [cited 2022 June 22]

64. Mason LH, Mathews MJ, Han DY. Neuropsychiatric symptom assessments in toxic exposure. Psychiatr Clin North Am. 2013 Jun;36(2):201-8. doi: 10.1016/j.psc.2013.02.001. Epub 2013 Apr 15. PMID: 23688687. [cited 2022 June 22]

65. Tewksbury A, Olander A. Management of antipsychotic-induced hyperprolactinemia. Ment Health Clin. 2016;6(4):185-190. Published 2016 Jun 29. doi:10.9740/mhc.2016.07.185 [cited 2022 June 24]

Originally Published on: Oct 30, 2018 by Diane Ridaeus

This content has been reviewed and approved by a licensed physician.

Dr. Samuel Lee

Dr. Samuel Lee is a board-certified psychiatrist, specializing in a spiritually-based mental health discipline and integrative approaches. He graduated with an MD at Loma Linda University School of Medicine and did a residency in psychiatry at Cedars-Sinai Medical Center and University of Washington School of Medicine in Seattle. He has also been an inpatient adult psychiatrist at Kaweah Delta Mental Health Hospital and the primary attending geriatric psychiatrist at the Auerbach Inpatient Psychiatric Jewish Home Hospital. In addition, he served as the general adult outpatient psychiatrist at Kaiser Permanente.  He is board-certified in psychiatry and neurology and has a B.A. Magna Cum Laude in Religion from Pacific Union College. His specialty is in natural healing techniques that promote the body’s innate ability to heal itself.

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