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Medications & Drugs That Cause Neurological Issues

Most medications are not completely understood as to how they impact the human body. This is an amazingly overlooked fact. Theories and conjecture and even untruths have enabled drug regulators to approve many drugs, while not actually understanding their mechanisms. What IS known, however, is that many drugs are linked to resulting neurological issues that can possibly be resolved once the drug is withdrawn.2

The term “encephalopathy” means brain damage whether it is caused by a disease, a toxin, a drug, genetic factors, or other causes. Researchers show that MANY drugs and toxins can cause encephalopathy.29

pharma drugs neurological side efffectsThe following are some of the drugs are known to cause neurological issues:

  • Benzodiazepines
  • Sedatives
  • Opioids
  • Amphetamines
  • Antidepressants
  • Antipsychotics
  • Alcohol
  • Recreational drugs

(Please scroll down for more info on each drug listed here.)

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Understanding how drugs can cause neurological issues remains elusive. Neurological issues impact our unimaginably complex nervous system that sends and manages messages throughout the entire body. The brain, the spinal cord, and the gut are 3 major hubs that coordinate and maintain healthy signal transmission throughout the entire system. Medications, recreational drugs, including alcohol, and environmental toxins can corrupt this finely tuned network, resulting in neurological issues, and even neurological damage.16,17,21,22


Poor nutrition, accumulated toxic load, and frequent or long-term drug use can all impair neural functioning, which can skew perception, thinking, behavior, sensation, and many other facets of human life.1,3,24 These are the very areas we address, helping our clients to achieve their mental health and recovery goals without having to rely on drugs to do so.
When do Medications Become the Bigger Problem?
neurological issues caused by meds & drugs

For about 2 decades, Alternative to Meds Center has used orthomolecular medicine, toxin removal, safe tapering, and a wealth of evidence-based therapies to return natural mental health to our clients, while benefiting from reduced or completely eliminated need for medication. Our consistent success is demonstrated by our long-term statistics which you are invited to review. For more information on medications and drugs that may be doing more harm than good, please read on.
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Benzodiazepines

Benzodiazepines are a central nervous system depressant, or sedative. This group of drugs, including Xanax (alprazolam), Klonopin (clonazepam), Ativan (lorazepam), Valium (diazepam), and others, is commonly used for treating short-term anxiety, panic attacks, and muscle spasms, and can be used to help with alcohol withdrawal. However, benzodiazepine drugs are often overprescribed far longer than the several weeks maximum that drug regulators have advised. Long-term use can cause debilitating damage to the brain and nervous system.4

Sedatives

While benzodiazepines are the primary group of sedatives used today, there are other drugs used to treat conditions like anxiety and insomnia. Central nervous system depressants include barbiturates like Luminal (phenobarbital) and insomnia drugs (or “Z-drugs”) like Ambien and Lunesta. Sedatives work similarly to alcohol — they interfere with neurotransmitters to decrease certain nervous and cognitive functions. As a result, sedatives can provide feelings of calm and euphoria in addition to inducing sleep.

After taking a sedative, individuals may experience several side effects such as slurred speech, inability to concentrate, headache, dizziness, confusion, hallucinations, slow breathing, low blood pressure, nightmares, paranoia, and mild euphoria. 

When taken long-term, researchers have noted that sedatives can cause neurological issues such as memory impairment, attention and concentration issues, decreased executive function, and risk of early onset of dementia.5,13,25

Opioid Painkillers

Opioid painkillers derived from the poppy plant or its analogs, are helpful for treating pain. Prescription opioids are also used to treat conditions as wide-ranging as severe cough to diarrhea.

Examples of prescribed opiates include Hydrocodone, oxycodone, oxymorphone, morphine, codeine, and fentanyl. All opioids are highly addictive and can quickly cause dependence and other side effects even when taken as prescribed.

When taken for prolonged periods, opioids can have uncomfortable and sometimes serious side effects, including feeling tired, drowsy, confused, nauseous, constipated, or euphoric. Misusing opioids can lead to slower breathing, which can result in hypoxia (too little oxygen reaching the brain). Hypoxia may lead to short-term or long-term neurological effects, such as a coma, permanent brain damage, or death. Studies have demonstrated that physical and chemical changes in the brain caused by opioids can also lead to a lowered seizure threshold, increased pain sensitivity, sleep disturbances, and hormonal imbalances.6

Amphetamines

Amphetamines are not only potent stimulants, they are neurotoxic. They are also highly addictive and associated with a wide range of side effects including psychosis, insomnia, euphoria, loss of appetite, and many others.7

Antidepressants

Selective serotonin reuptake inhibitors (SSRIs) and other types of antidepressants, such as amitriptyline can cause side effects like nausea, dizziness, sleep issues, and fatigue throughout the course of treatment. These drugs can lead to functional neurological disorders as these symptoms linger and may become permanent. Some antidepressants can cause NMS (neuroleptic malignant syndrome), and serotonin syndrome. Both of these conditions are potentially life-threatening, with symptoms of confusion, high fever, muscle rigidity, increased heart rate, coma, and others.8,27,29,30

Antipsychotics

Antipsychotics serve their purpose well in managing acute mania, psychosis, and schizophrenic symptoms. However, their clinical history is plagued by imperfect diagnoses, and unnecessarily long-term use. Research over many decades has documented the link between antipsychotics and undesirable neurological issues such as NMS, seizures, stroke, and other major complications, and equally so or even worse, when trying to withdraw from them.9-12

Alcohol

Research on alcohol related brain damage has documented the devastating neurological issues associated with chronic alcohol use, including amnesia, damage to brain structure, schizophrenic symptoms, and many others. Safe withdrawal from alcohol must be done in a supervised, medical setting due to the high risk of seizure and potential death if not managed properly.18

Drug-Induced Neurologic Conditions — Summary

Most notably after long-term use, and addiction, a wide range of neurological issues are linked to drugs, medications, and alcohol.4,6,8,14,15,20,25,28

drug-induced brain effectsDrug-induced neurological issues can include:

  • Stroke
  • Dementia
  • Seizures
  • Ataxia
  • Akathisia
  • Encephalopathy
  • Memory loss
  • Suicidal behavior/thinking
  • Aggressive, violent behavior
  • Involuntary movement disorders

Drug-Induced Strokes

According to the WHO, stroke is the second leading cause of death and disability in today’s world.10 Drugs known to contribute to increasing the risk of stroke include antipsychotics, and long-term or high dosage benzodiazepines.11,12

Drug-Induced Dementia

Dementia includes many neurological issues that involve degenerative cognitive function. A common symptom is poor memory, which progresses into inability to speak or process what is being said, inability to concentrate, inability to make decisions or plans, and poor visual-spatial capabilities.

According to broad research published in the 2022 British Medical Journal it was found that of 744 medications studied, one third of these prescription medications were linked to dementia.

The medications referenced in the study include benzodiazepines, sleeping pills, opiates and other pain pills, drugs used for quitting smoking, and many other classes of medications.13,25

Drug-Induced Seizures

Seizures are another neurological issue that can result from both pharmaceutical and street drugs. Seizures occur with an electric burst or other electrical disruption within the brain. Seizures disrupt processing thoughts, awareness, memory, muscle control, and movement. When a seizure happens, a person may stare into space, go limp, or start jerking or convulsive motions. Alcohol use disorder has a definite link to incidence of seizures. Drugs that can cause high or low blood sugar, high or low sodium plasma levels, or lack of oxygen from depressed respiration or heart rate, or sleep deprivation are all linked to seizure activity. Benzodiazepine withdrawal and alcohol withdrawal can cause seizures if not managed properly.31,32

Among the drugs most responsible for inducing seizures are the antidepressants and antipsychotics, including escitalopram (Cymbalta), bupropion (Wellbutrin), clozapine (Clozaril), quetiapine (Seroquel), and many others.14

Seizures have occurred in cases of opioid withdrawal, and a synthetic opioid called Tramadol lowers the threshold for seizures according to clinical research.31

Stimulant drugs such as the amphetamines, ecstasy, and cocaine cause seizures. Withdrawing abruptly from certain substances, such as alcohol or benzodiazepines, can result in serious seizures, which can sometimes be fatal.15

Drug-Induced Ataxia

Ataxia is a condition of the central nervous system in which individuals experience trouble with coordination and movement. Drugs and toxins can injure the parts of the brain that control these functions. Those so affected may appear drunk, with slurred speech, may fall or stumble, or appear uncoordinated. These symptoms occur due to damage to the cerebellum, the part of the brain that controls movement.9,28,33

Drugs and environmental toxins can cause ataxia to develop, including:
  • Alcohol
  • Antiepileptic drugs
  • Addictive drugs like cocaine, heroin, PCP (angel dust)
  • Environmental toxins like mercury, lead, manganese, toluene, benzene
  • Sedatives like barbiturates and benzodiazepines
  • Antipsychotics like lithium
  • Inhalants
  • Antineoplastics (used in treating cancer)

Drug-Induced Encephalopathy, Hypoxia

Encephalopathy (brain damage, malfunction, or disease) can result from structural damage, lesions, or other causes such as poor oxygen supply to the brain. In drug-induced cases, the damage done to the brain may be reversed by safely withdrawing from the drug. However, in some cases, there is too much damage that limits recovery. Additionally, encephalopathy can occur from the use or overuse of drugs that affect the function of the vital organs, cause chronic disturbances of consciousness, memory loss, uncontrolled seizures, personality changes and many other symptoms. 29

Drugs that are linked to causing encephalopathy include antibiotics, alcohol, antipsychotics, anticonvulsants, opioids, lithium, benzodiazepines, and stimulants such as cocaine. Drug-induced encephalopathy has been linked to many drugs that slow breathing, limiting oxygen sent to the brain (hypoxia). Timely treatment when little or no oxygen has reached the brain is critical to avoid permanent neurological damage. In many cases, this and other types of neurological damage often reverses when the drug is correctly withdrawn.19,29

Drugs That Cause Neurological Issues FAQs

If you are currently taking prescription medications, you may be concerned about potential neurological issues. These frequently asked questions could help you determine whether you should seek alternative therapy.

What are the Most Common Drugs that Cause Neurological Disorders?
The most commonly linked drugs to neurological issues are alcohol, antidepressants, opiates, benzodiazepines, amphetamines, recreational drugs, and sedatives. Any drug or other toxic chemical that depresses or impairs the central nervous system can potentially contribute to brain damage and other neurological issues.25
What Is the Number One Most Common Drug-related Neurological Issue?
There are many of these, but strokes and seizures are reportedly very common drug-related neurological issues.14,20
What Chemicals Can Cause Neurological Problems?
Neurotoxicity refers to damage of the brain or nervous system due to exposure to certain chemicals. These toxic chemicals can kill or disrupt the neurons vital to the proper processing of chemical messages. Some chemicals can cause great damage to the nervous system.& In modern times we are over-exposed to toxic chemicals in our food, medicine, water, the soil, the air, cleaning products, industrial products, and many others.21,22

Some chemicals that can cause neurotoxicity are:
  • Chemotherapy drugs
  • Heavy metals, such as cadmium, lead, manganese, toluene, benzene, and mercury
  • Insecticides and pesticides
  • Cosmetics
  • Industrial cleaning products
  • Addictive street drugs
  • Pharmaceutical medications

If you have suffered from neurotoxicity, you may have experienced physical pain, muscle weakness, altered mood, emotional distress, memory loss, cognitive decline, or other overlapping psychiatric and physical symptoms. There is a wide range of such distressing neurological symptoms such as tingling or numbness in the limbs, headache, loss of sight, behavioral issues, sexual issues, depression, poor circulation, and dizziness.26

How Does Nutrition Impact Mental Health?
Nutrition plays a very key role in restoring mental health, regardless of other factors that may have contributed to neurological issues. A prime example is that a deficiency of magnesium has been found directly linked to elevated psychological stress.23

Nutrition is a HUGE part of successful therapeutic results at Alternative to Meds. Educational modules are provided to clients to increase their knowledge and application to their healing journey. Restoring nutrient levels can significantly proof the body against assaults from many environmental sources and can also help in healing after acquired neurological issues that arose from toxins of various types.24

Contact Alternative to Meds Center for Help

Are you concerned about healing from or reducing the risks of drug-induced neurological issues? We’ve been working this problem for many years with much success. And we have established a great number of ways to safely and comfortably assist our clients to regain natural mental health. We apply extensive lab testing, orthomolecular medicine to correct the diet and restore nutrient deficiencies, environmental medicine to remove toxins, and safe tapering to come off the medications/drugs that could be contributing to neurological issues. You can call us for more information about the program, insurance coverage, length of program, or any other questions you may have and we will be happy to take the time to speak with you. Call today!

1 (800) 301-3753 for Help with Drugs that Cause Neurological Issues

References:

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This content has been reviewed and approved by a licensed physician.

Dr. Samuel Lee

Dr. Samuel Lee is a board-certified psychiatrist, specializing in a spiritually-based mental health discipline and integrative approaches. He graduated with an MD at Loma Linda University School of Medicine and did a residency in psychiatry at Cedars-Sinai Medical Center and University of Washington School of Medicine in Seattle. He has also been an inpatient adult psychiatrist at Kaweah Delta Mental Health Hospital and the primary attending geriatric psychiatrist at the Auerbach Inpatient Psychiatric Jewish Home Hospital. In addition, he served as the general adult outpatient psychiatrist at Kaiser Permanente.  He is board-certified in psychiatry and neurology and has a B.A. Magna Cum Laude in Religion from Pacific Union College. His specialty is in natural healing techniques that promote the body’s innate ability to heal itself.

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Nothing on this Website is intended to be taken as medical advice. The information provided on the website is intended to encourage, not replace, direct patient-health professional relationships. Always consult with your doctor before altering your medications. Adding nutritional supplements may alter the effect of medication. Any medication changes should be done only after proper evaluation and under medical supervision.

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