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Sedatives: Dependence, Withdrawal, & Alternatives

Sedative side effects are similar among many drugs including tranquilizers and hypnotics and other calming agents, all of which may have a risk for developing dependence, and all of which may have alternatives that are safer and do not develop dependence or withdrawal symptoms.
There can be some overlap of drugs between the sedative class, benzodiazepine class, tranquilizers, hypnotics, and anxiolytics. However, while some drugs fit into multiple classifications of drugs, there are several drugs, called Z-drugs, that only fit into the sedatives class. These include Intermezzo, Sonata, Ambien, and Lunesta.

What Are the Types of Sedative Drugs & Medications?

Click on the type of sedative below to learn more. We provide general and clinical information on these drugs, as well as FAQs, resources, and clinical information on safely quitting sedatives, easing sedative withdrawal, and assistance on how to safely taper sedative drugs to share with your prescriber.

Sedatives Medication FAQs

Because a number of drugs can fit into the class of sedatives, we have included general questions and answers about the sedative class of drugs below, as well as specific questions about Z-drugs.

Have a question about prescription sedatives we didn’t cover? Contact us and our knowledgeable professionals can answer your questions.

What are Z-Drugs?

Z-drugs are non-benzodiazepine drugs that are often used to treat insomnia and other sleep disorders. They also have been used “off label” for anxiety, restless leg syndrome, and a host of other experimental treatments. Common “Z” drugs include zaleplon (Sonata®), zolpidem (Ambien®), zopiclone (Imovane®), and eszopiclone (Lunesta®).
Medical Disclaimer:
Nothing on this Website is intended to be taken as medical advice. The information provided on the website is intended to encourage, not replace, direct patient-health professional relationships. Always consult with your doctor before altering your medications. Adding nutritional supplements may alter the effect of medication. Any medication changes should be done only after proper evaluation and under medical supervision.

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