Prescription Medications Influence Nutrient Requirements

Prescription medications can impact the nutrient levels present in the body as well as how the body processes nutrients. Long-term use of prescription medications can lead to deficiencies of essential vitamins and minerals in the body, referred to as a drug-nutrient interaction.1 More specifically, a drug-nutrient interaction refers to any physical, chemical, physiologic, or pathophysiologic response between a drug and a nutrient.2
Don’t be afraid to talk in-depth with your medical doctor about the potential drug-nutrient interactions you may encounter from the medication you are currently taking. This information is necessary for you to begin holistic detoxification safely.
How Does Nutrition Affect Your Medication?
Your doctor or pharmacist should advise you about potential drug-nutrient reactions between the foods you consume and the prescription medications they place you on to treat your condition.3 The food you consume can have a tremendous impact on the medications you’re currently taking. The foods in your diet can cause your medication to work slower or faster than needed. Some medicines even interact with food, preventing your medication from ever working at all.
Which Medications Deplete Nutrients?
All medications slowly deplete your body of essential nutrients over time, a fact that should be concerning to anyone who takes prescription medicine long-term. If you already lack nutrients in your body from a poor diet, you can face increased risks of deficiencies if you also need to take prescription medication.
You should know which types of medications deplete nutrients so that you can begin to supplement your diet with the foods that will help restore your body to balance. This knowledge will help you prevent nutrient depletion as you start to detox or taper down your use of prescription medication.
The following classes of medications are the top 5 types reported to deplete your body of needed nutrients with long-term use. Please understand that this list is not exhaustive, as chronic diseases like heart disease, cancer, diabetes, stroke, and arthritis also require prescription medications that deplete nutrients in the body over time.
Proton Pump Inhibitors (PPI)
- Omeprazole (Prilosec)
- Esomeprazole (Nexium)
- Pantoprazole (Protonix)
Proton pump inhibitors are medications that lower the amount of acid produced in the stomach and are used to treat the symptoms common in acid reflux and gastroesophageal reflux disease (GERD). These drugs specifically deplete the body of nutrients vitamin B12, vitamin C, calcium, iron, and magnesium.
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Opioids
- Oxycodone
- Hydrocodone
- Morphine
- Hydromorphone
Opioid use depletes the body of folic acid, vitamin C, potassium, and iron.
Psychotropic Medications
- Antidepressants (Paxil, Nortriptyline, Prozac, Buspar, Bupropion, etc.)
- Antipsychotics (Lithium, Quetiapine, Abilify, Clozapine, etc.)
Medications prescribed to help people manage psychological disorders cause the body to have depleted levels of niacin, vitamin D, calcium, coenzyme Q10, and folate.
Antibiotics
- Amoxicillin
- Cephalexin
- Azithromycin
- Doxycycline
- Vancomycin
Antibiotic medications deplete the body of nutrients including calcium, magnesium, and potassium. B vitamins (B1-thiamin, B2- riboflavin, B3-niacin, B5-pantothenic acid, B6, B9-folic acid, B12) and vitamin K become depleted as well.
Blood Pressure Medications
- Furosemide
- HCTZ
- Spironolactone
Medications that lower blood pressure typically deplete the body of magnesium, sodium, potassium, zinc, pyridoxine, thiamine, and ascorbic acid with prolonged use.
Arming yourself with knowledge about the classes of medications of drugs and the types of nutrients they deplete gives you a roadmap for supplemental nutrition. You can use this information on your journey to treat health issues as you go through your holistic detox.