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Remeron Tapering (Mirtazapine)

Alternative to Meds Center offers safe and comfortable Remeron tapering programs. Using antidepressants can quickly devolve into a nightmare of such suffering that even the most unread in the medical field are only now waking up to the severity of the problem. Most physicians do not know how to help. 

One of the more popular reasons for stopping Remeron is because its side effects begin to outweigh any perceived benefits. Getting off Remeron may be the only logical choice where the drug has so often utterly failed in expected treatment results.

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remeron titration
Alternative to Meds has been a Remeron withdrawal help authority for more than 15 years. We have published evidence regarding our success. Even if the person had what might be considered highly atypical symptoms, these same symptoms are much more common than what is being admitted to. The reason we specialize in these symptoms is because many of us have also had to endure them ourselves in order to become the teachers that we are.
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Many persons have been misdiagnosed. Misdiagnosis is arguably the most common reason for considering withdrawal from Remeron. The DSM V (prescribing manual) recently upgraded the necessary criteria that would indicate antidepressants as a valid treatment. Thus, some patients had been put on Remeron in error, and now desire to begin Remeron tapering because antidepressant medication wasn’t the right choice to begin with.1

One example revolves around PTSD. The criteria for diagnosing a person with PTSD have changed a few times. A diagnosis of PTSD may have been hasty or premature. Some exclusions might be where a person has experienced death in the family, or when a close friend dies.1 Other examples of exclusions could be when symptoms are caused by medications, illness, or substance abuse. These would be (should be) exclusions. But often, these exclusions are missed entirely, hanging a person with a diagnosis that is not accurate, and a drug that will not help. Remeron tapering may be indicated especially where the accuracy of a PTSD diagnosis was unclear or incorrect.

If you feel you may have been prescribed antidepressant medication unnecessarily, you may wish to speak about it further with your prescribing physician. One can find out more about what steps are needed for antidepressant tapering. It is recommended that a person not delay in seeking this medical assistance. This is because the longer one remains on medication, especially where it was not the correct treatment to begin with, the more complex the process of getting off Remeron. 

Learning More About How to Get Off Remeron

In terms of side effects, there can be many of these and they may be different for each individual in character, and also intensity can vary widely. Some side effects may be mild for one person, and intolerable for another. However, below are outline just some examples of what may lead a person to choose to withdraw from Remeron. Learning more about how to get off Remeron may be a wise choice where:

  • Mild side effects have begun negatively affecting the person’s quality of life, such as dry mouth, ulcers in the mouth, swelling of the lips or tongue, drooling, bleeding gums, loss of ability to taste, indigestion, altered sensations of taste, smell, etc.
  • A person may experience more serious health concerns due to more severe side effects, such as vomiting, bleeding intestines, worsened depression, sleep disturbances, agitated. edgy or irritated feeling, shaking, flu-like symptoms (cough, fever, sore throat, headache), anger, twitching, restless legs, anxiety, back pain, muscle pain, etc.
  • Side effects have become extremely severe and in some cases may become life-threatening such as suicidality, akathisia, mania, confusion, pancreatitis, convulsion, stupor, and other severe adverse reactions.
  • A woman who becomes pregnant or plans to become pregnant may be concerned regarding the increased chance of miscarriage and premature birth that occur among mothers taking Remeron during pregnancy.2

remeron tapering

Remeron Titration Should Never be Done Abruptly

There can be many reasons for stopping Remeron. Probably just about as many as there are individuals who started taking the drug. However, there is one point that is absolutely critical. And that is to avoid stopping Remeron abruptly. Getting off Remeron safely requires a very gradual and gentle approach, with qualified medical oversight and monitoring throughout the process of Remeron tapering. With these cautions in place, Remeron tapering can be successfully completed without lingering symptoms of withdrawal. One will suffer from lingering withdrawals especially where the process of Remeron tapering was done too quickly. The body would not have been allowed the time needed to adjust and normalize. And that would be painful to endure. 

Remeron Tapering Made Simpler, Safer, Easier to Tolerate

The Alternative to Meds Center provides an amazingly comprehensive treatment program that consists of too many segments to describe in this short article. But there are 5 main categories into which these therapies are organized. 

  1. Neurotoxin testing and removal by non-invasive and natural methods such as low-temperature sauna, castor oil packs, nebulized glutathione, mineral detox foot baths, and many other treatments. 
  2. Dietary and nutritional corrections, orthomolecular and environmental medicine, etc., for enhancing neurochemistry replacement and improved energy, mood, etc.
  3. Natural Remeron alternatives that effectively replace prescription medicine, handle sleep issues, etc. without toxic drugs.
  4. Therapies for physical pain relief and healing as well as to provide mental and emotional comfort such as Reiki, craniosacral massage, life coaching, CBT, equine-assisted therapy, soothing mineral baths, acupuncture, gentle exercise classes (trainer-led), stress reduction techniques, and many, many more.>
  5. There is also an educational component to the program where clients learn about neurochemistry, diet and mood, how toxic food additives harm the CNS/brain, the gut-brain connection and how to protect it, and much more. 

WARNING: NEVER ABRUPTLY ATTEMPT GETTING OFF REMERON. EVEN THE FDA CAUTIONS THAT TO DO SO CAN RESULT IN SIGNIFICANT RISKS TO HEALTH. There are safer and more gradual ways that can ease the process of Remeron titration without endangering one’s health.3

Additional Notes on Remeron 

Remeron is an antidepressant drug in the tetracyclic class, meaning its atomic structure consists of 4 rings rather than the 3 rings of other antidepressants. This is why, in part, Remeron is referred to as an “atypical” antidepressant, because it is believed that it has characteristics that are quite different from other types or classes of antidepressants. And, important to note, it is not known exactly how it creates the effects that it does in the brain and CNS. There are some indications suggesting Remeron affects the histamine receptors, adrenaline receptors plus dopamine, and serotonin receptors. But it is not exactly understood how these all interact exactly. At low doses, Remeron often has more of a sedative effect. At higher doses, the drug tends to have a stimulating effect.

How Long Does Remeron Tapering Take? 

Remeron has a complex structure and side effect profile. Various potential interactions and reactions will be undergoing flux while a person attempts to normalize their neurochemistry during Remeron tapering. An adequate time frame in which to complete the Remeron cessation comfortably will be of great importance. The length of time for Remeron tapering can vary, such as for a person who has already tried to quit but was balked by the intensity of withdrawals.The person will do much better with enough time allowed to safely complete their Remeron taper. 

help getting off remeronThe Alternative to Meds Center Remeron tapering programs recommend that the client enrolls for 60 days, on average, although a longer stay can be arranged if requested. Our goal at the center is to provide the means for our clients to achieve natural mental health. Clients are given a program that is designed to test for and address any possible factors that may have contributed to unwanted symptoms that were troubling the person before starting to take prescription medications. This approach is supported by nutritional testing and correction of deficiencies, neurotoxin testing and removal, and addressing many other factors that may have never been previously addressed, and that could have lead to seeking relief through unnecessary medication.

Please contact Alternative to Meds Center for a much more detailed description of our inpatient Remeron tapering programs and what benefits are available to our clients who wish to improve their natural mental health.


1. Truschet E, “Depression Definition and DSM 5 Diagnostic Criteria”  Remedy Health Media [INTERNET] March 2019, updated November 25, 2019 [cited 2020 Jun 4].

2. “Exposure to mirtazapine during pregnancy, a prospective, comparative study of birth outcomes” Article published by US National Library of Medicine August 2006, PubMed, [cited 2020 Jun 4].

3. Shelton R MD “Steps Following Attainment of Remission- Discontinuation of Antidepressant Therapy” US National Library of Medicine” [cited 2020 Jun 4].



This content has been reviewed and approved by a licensed physician.

Dr. Samuel Lee

Dr. Samuel Lee is a board-certified psychiatrist, specializing in a spiritually-based mental health discipline and integrative approaches. He graduated with an MD at Loma Linda University School of Medicine and did a residency in psychiatry at Cedars-Sinai Medical Center and University of Washington School of Medicine in Seattle. He has also been an inpatient adult psychiatrist at Kaweah Delta Mental Health Hospital and the primary attending geriatric psychiatrist at the Auerbach Inpatient Psychiatric Jewish Home Hospital. In addition, he served as the general adult outpatient psychiatrist at Kaiser Permanente.  He is board-certified in psychiatry and neurology and has a B.A. Magna Cum Laude in Religion from Pacific Union College. His specialty is in natural healing techniques that promote the body’s innate ability to heal itself.

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