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Vraylar Alternatives | Your Natural Arsenal to Boost Mental Health

Last Updated on January 9, 2024 by Carol Gillette

Alternative to Meds Editorial Team
Medically Reviewed by Dr Samuel Lee MD

Vraylar alternatives might be a better choice for improvements in mental wellness. Vraylar is a relatively new antipsychotic drug, that has been approved for treating schizophrenia, and as an add-on medication in treating episodic bipolar mania and depression.1

it may be a good time to consider alternatives to Vraylar that may be less risky compared to using heavy medication for long periods of time. We recommend speaking to your prescriber before making such changes and becoming more knowledgeable about treatments that are available today that are not associated with adverse consequences.

Do Your Symptoms Require Vraylar?
holistic antipsychotic alternatives

For nearly 20 years, Alternative to Meds Center has been a world leader in providing safer Vraylar alternatives, delivered in a pristine facility overlooking the Red Rock Mountains near Sedona Arizona. Thousands of our clients have had great success as shown in our independently researched performance study. We are passionate about what we do. We can help you design your personalized pathway to improved mental health if you are looking for less toxic methods using Vraylar alternatives. This might appeal to anyone hoping for more effective treatment results in the long run, and for a brighter future for yourself or for a loved one.

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About Vraylar

Vraylar may be less sedating and is associated with less weight gain than some other antipsychotics. Some adverse effects may emerge with this drug, however, more often than some others in its class. Antipsychotics generally have a very long half-life, and this is certainly true for Vraylar, about 2-4 days, according to the label. As the drug builds up in the system, this may, in part, explain why some people experience late-occurring adverse effects that didn’t show up in short-term safety trials. No safety trials were done for pregnancy in humans, though birth defects did appear in animal studies. Babies born to mothers taking Vraylar may suffer postpartum distress of various kinds. These and other cautions are listed on the drug label.1

why is vraylar prescribedVraylar is classed as an antipsychotic for treating schizophrenia but has also been approved as an adjunctive medication in cases of bipolar depression or mania. The generic drug is cariprazine. Cariprazine’s mechanism of action is “unknown,” but is thought to either bind to or block certain receptors (dopamine and serotonin receptors). Many drugs come to market without knowing their mode of action. Anti-seizure drugs, for example, may suppress symptoms, but their MOA (mechanism of action) is unknown and cannot actually modify the underlying disease. Drug-based therapy for mental health is based nearly exclusively on the suppression of symptoms, and not on correcting the underlying causes.

We do know the exact mechanisms of action of other substances, such as vitamin C, and eating greens. It is something of a mystery how for close to 200 years now, the vast majority of medical drugs have been approved for public consumption without industry regulators requiring this missing vital information.2-4

Physicians stopped using “magical spells” a long time ago, perhaps replaced by a well-intentioned wish that a drug could be the magic bullet for mental health.12 Let us hope that we can continue to move away from lingering habits such as relying on poorly understood medications — especially when reliable Vraylar alternatives are plentiful, more completely understood, and safer.

Why Consider Vraylar Alternatives?

The hope is that taking a prescription drug will alleviate unwanted symptoms. The 2 main reasons one might consider alternatives to prescription drugs are that they didn’t work as hoped and that they caused new unwanted symptoms to emerge.

Please remember it is unsafe to abruptly discontinue a drug you’ve been taking for a period of time, (and especially antipsychotic medication) without medical oversight and a plan in place to safely and gradually discontinue taking it. Always coordinate with your prescribing physician before making changes to your drug regimen.5

If you have unwanted symptoms but have not started on Vraylar, alternatives are available that have proven efficacy, known mechanisms of action, and most importantly, are safe and non-toxic, with long-lasting efficacy. Specific examples of these are discussed below.

Before Starting Vraylar

If circumstances permit, (i.e., you are not in the middle of a crisis) don’t hesitate to ask for lab testing and analysis before accepting a prescription. In this way, it is possible to get a more complete snapshot of what’s going on internally, and what may need to be corrected.

investigate root causesIn the case of considering a Vraylar prescription, it is likely that even when other drugs had been tried before and found unsatisfactory, perhaps the whole situation was underscored by an imperfect diagnosis in the first place. It is not always possible to get a perfect diagnosis. Many “symptom overlaps” can occur and can even wax and wane over time making anything close to an accurate conclusion very hard to reach, especially true in the rush of a 5- or 10-minute doctor’s appointment. It is also very likely that no or too little lab testing has been done to help zone in on the exact set of contributing factors that may need correcting.

Alternative to Meds Center is not interested in getting a label to slap on the situation but is focused on investigation using all possible tools, to find the root causes of symptoms. Then, using alternatives to medication, the goal becomes to correct or rebalance or remove the culprits. This is easiest done before starting a prescription but can still be done even if already taking antipsychotics, as will be described further below.

Already Taking Vraylar?

Antipsychotics can be quite tricky to withdraw from. The process may take time but it can be done, and in some cases, the medication can be reduced to zero. But this is not always possible. A well-stated goal might be to safely reduce medication to the lowest viable dosage and still retain a satisfactory quality of life. Alternatives to Vraylar can be surprisingly effective when used under medical monitoring, and with adequate preparation and step-by-step support and instruction along the way.

The Elusive Root Causes for Unwanted Symptoms

Our clients have benefited greatly from a comprehensive process of discovery, utilizing laboratory testing, analyses, and other assessments that can inform the most logical and effective ways to proceed.

Some of the most prevalent culprits we have found include accumulations of neurotoxins, poor diet leading to nutritional deficits, food or other allergies, helpful lifestyle restructuring, unhandled past trauma, past drug or alcohol use, and a wide range of others. These contributing factors don’t go away by taking a drug. They need to be actually fixed or changed proactively. That is our mission, to bring an end to unwanted symptoms without relying solely on prescription medication to do so. Some persons can completely come off their medication, and others can reduce their dosage to the minimum possible while retaining a desirable overall satisfactory quality of life. The natural alternatives to Vraylar can provide a bridge back to improved mental health, without solely relying on medications.

Treating the Causes vs Masking Symptoms

Many science-based alternatives to Vraylar are used inpatient at Alternative to Meds Center to help clients focus on achieving their health goals. The approach is straightforward and highly effective, according to the successes we see every day, and according to many clinical trials showing efficacy for these methods. Targets might include improving quality of sleep, reduced depression and anxiety, pain relief, and other benefits.7-10

Alternatives to Vraylar can include:

neurotransmitter rehabilitation key to getting off drugs

Alternative to Meds Center Provides Science-Based Alternatives to Vraylar

Inpatient treatment at the center provides positive peer support as well as oversight by over 50 trained and licensed mental health professionals and therapists. High-quality peer support programs are a huge benefit not always accessible in outpatient programs.11 Our programs are thorough and comprehensive. Insurance coverage can help reduce costs in many cases. Clients receive individual programming, which is designed to accomplish several fundamental goals. vraylar holistic alternatives sedona drug rehabNeurotoxins need to be cleaned out using chelation, sauna cleanse, colon hydrotherapy, and other gentle but effective methods.6

Stabilizing the neurochemistry is achieved using natural substances, and nutritional therapy, including vitamins, minerals, amino, herbal and food-based remedies. Restoring gut health — a functioning microbiome — is essential to mental and physical wellness.13 Physical therapies provide comfortable, nurturing support and may accelerate healing.

In a calmer, well-rested state of comfort, medication can then be slowly reduced, with attentive monitoring all the way through. Counseling is on-site to provide additional stabilization and freedom from troublesome or lingering conditions of the past. Planning the future then becomes a hopeful, positive natural outcome. These and other natural alternatives to Vraylar can all help ensure success. Please call us today to discuss your personal goals, and to get more information on the potential benefits of such a program for you or your loved one.


1. FDA label Vraylar (cariprazine) capsules, for oral use [approval date XXXX] [cited 2023 Jan 14]

2. Davis RL. Mechanism of Action and Target Identification: A Matter of Timing in Drug Discovery. iScience. 2020 Aug 21;23(9):101487. doi: 10.1016/j.isci.2020.101487. Epub ahead of print. PMID: 32891054; PMCID: PMC7479624. [cited 2023 Jan 14]

3. Abdullah M, Jamil RT, Attia FN. Vitamin C (Ascorbic Acid) [Updated 2022 Oct 25]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: [cited 2023 Jan 14]

4. Sills GJ, Rogawski MA. Mechanisms of action of currently used antiseizure drugs. Neuropharmacology. 2020 May 15;168:107966. doi: 10.1016/j.neuropharm.2020.107966. Epub 2020 Jan 14. PMID: 32120063. [cited 2023 Jan 14]

5. Keks N, Schwartz D, Hope J. Stopping and switching antipsychotic drugs. Aust Prescr. 2019 Oct;42(5):152-157. doi: 10.18773/austprescr.2019.052. Epub 2019 Oct 1. PMID: 31631928; PMCID: PMC6787301. [cited 2023 Jan 14]

6. Genuis SJ. Toxic causes of mental illness are overlooked. Neurotoxicology. 2008  Nov;29(6):1147-9. doi: 10.1016/j.neuro.2008.06.005. Epub 2008 Jun 24. PMID: 18621076. [cited 2023 Jan 14]

7. Bremner JD, Moazzami K, Wittbrodt MT, Nye JA, Lima BB, Gillespie CF, Rapaport MH, Pearce BD, Shah AJ, Vaccarino V. Diet, Stress and Mental Health. Nutrients. 2020 Aug 13;12(8):2428. doi: 10.3390/nu12082428. PMID: 32823562; PMCID: PMC7468813. [cited 2023 Jan 14]

8. Woodyard C. Exploring the therapeutic effects of yoga and its ability to increase quality of life. Int J Yoga. 2011 Jul;4(2):49-54. doi: 10.4103/0973-6131.85485. PMID: 22022122; PMCID: PMC3193654. [cited 2023 Jan 14]

9. Zhang Z, Li S, Meng H, Wang Y, Zhang Y, Wu M, Chen Y, Rong P, Wang Y. Efficacy and safety of acupuncture in the treatment of depression: A systematic review of clinical research. Anat Rec (Hoboken). 2021 Nov;304(11):2436-2453. doi: 10.1002/ar.24783. Epub 2021 Oct 8. PMID: 34623754. [cited 2023 Jan 14]

10. Romero K, Goparaju B, Russo K, Westover MB, Bianchi MT. Alternative remedies for insomnia: a proposed method for personalized therapeutic trials. Nat Sci Sleep. 2017 Mar 17;9:97-108. doi: 10.2147/NSS.S128095. PMID: 28360539; PMCID: PMC5364017. [cited 2023 Jan 14]

11. Richard J, Rebinsky R, Suresh R, Kubic S, Carter A, Cunningham JEA, Ker A, Williams K, Sorin M. Scoping review to evaluate the effects of peer support on the mental health of young adults. BMJ Open. 2022 Aug 4;12(8):e061336. doi: 10.1136/bmjopen-2022-061336. PMID: 35926986; PMCID: PMC9358944. [cited 2023 Jan 14]

12. Moncrieff J. Magic bullets for mental disorders: the emergence of the concept of an “antipsychotic” drug. J Hist Neurosci. 2013;22(1):30-46. doi: 10.1080/0964704X.2012.664847. PMID: 23323530; PMCID: PMC4118918. [cited 2023 Jan 14]

13. Clapp M, Aurora N, Herrera L, Bhatia M, Wilen E, Wakefield S. Gut microbiota’s effect on mental health: The gut-brain axis. Clin Pract. 2017 Sep 15;7(4):987. doi: 10.4081/cp.2017.987. PMID: 29071061; PMCID: PMC5641835. [cited 2023 Jan 14]

Originally Published January 16,2023 by Diane Ridaeus

This content has been reviewed and approved by a licensed physician.

Dr. Samuel Lee

Dr. Samuel Lee is a board-certified psychiatrist, specializing in a spiritually-based mental health discipline and integrative approaches. He graduated with an MD at Loma Linda University School of Medicine and did a residency in psychiatry at Cedars-Sinai Medical Center and University of Washington School of Medicine in Seattle. He has also been an inpatient adult psychiatrist at Kaweah Delta Mental Health Hospital and the primary attending geriatric psychiatrist at the Auerbach Inpatient Psychiatric Jewish Home Hospital. In addition, he served as the general adult outpatient psychiatrist at Kaiser Permanente.  He is board-certified in psychiatry and neurology and has a B.A. Magna Cum Laude in Religion from Pacific Union College. His specialty is in natural healing techniques that promote the body’s innate ability to heal itself.

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Nothing on this Website is intended to be taken as medical advice. The information provided on the website is intended to encourage, not replace, direct patient-health professional relationships. Always consult with your doctor before altering your medications. Adding nutritional supplements may alter the effect of medication. Any medication changes should be done only after proper evaluation and under medical supervision.

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