Depakote Side Effects

Depakote Side Effects

Depakote side effects present alarming consequences for a wide range of age groups and also some specific populations.


The drug acts as an anticonvulsant, and has become the most frequently prescribed antiepileptic drug in the world. Additionally, the medication is also prescribed to treat migraine headaches, bipolar, and to prevent seizures which are non-epileptic in nature. How the drug works is not 100% known, but one theory is that it may, at least temporarily, increase the availability of GABA, which is an inhibitory neurotransmitter. This produces the sedating effect. 

One of the most troubling problems with Depakote that should deter pregnant women is that the drug causes birth defects such as spina bifida at the rate of three times the norm. Also, in young children and adolescents, this drug has been shown to cause "growth plate ossification," a condition causing decreased height. This medication causes another condition called "development delay" in the young, resulting in such distorted facial features as flattened nose, thickened lower lip, etc. Women would be well-advised to inform themselves as thoroughly as possible before taking any medications that may adversely affect them or harm their unborn children, especially where these effects may inflict permanent damage to their children. 

In the elderly, the majority taking Depakote have to deal with increased sleepiness, dizziness, and weight loss due to a suppressed appetite and nausea. Reportedly, most desire to stop taking the drug for these reasons, however, it can be dangerous to withdraw the drug abruptly. Sadly, physicians are not, in the main, adequately trained to help their patients accomplish this task safely. Alternative to Meds Center can help adults by treating Depakote side effects as well as provide safe, monitored tapering methods in a clinical setting. At the same time, we aim to stabilize and normalize the client's neurochemistry with holistic, health restorative therapies  

More Common Side Effects of Depakote:

  • Dementia
  • Confusion
  • Suicidality
  • Paranoia
  • Depression
  • Tremors, shaking
  • Personality changes
  • Dizziness, feeling lightheaded 
  • Black tarry stools, blood in stools, diarrhea
  • Delusions, seeing things that are not there
  • Lip smacking, puckering
  • Lower back or side pain
  • Leg cramps
  • Burning, crawling, prickling skin sensations
  • Bleeding gums, nosebleeds, unusual bruising
  • Fever or chills
  • Depersonalization
  • Euphoria
  • Tachycardia (racing heart)
  • Dysphoria (restlessness, inability to be still, agitation, relentless internal unease)
  • Loss of appetite, Anorexia
  • Insomnia, trouble sleeping, unusual dreams
  • Swelling of face, hands, feet, limbs, etc.
  • Coughing, hoarseness, sore throat 
  • Nervousness, anxiety
  • Rapid mood changes
  • Headache
  • Unusual sleepiness, tiredness
  • Weakness
  • Slurred speech
  • Difficult or painful urination
  • Impulsive, uncharacteristic actions and behaviours
  • Nausea and vomiting
  • Weight loss or weight gain (can be rapid)
  • Laboured breathing

WARNING: The FDA cautions against stopping anticonvulsant meds abruptly. To do so may cause seizure or other health problems. 

Treatment for Adverse Depakote Effects

The Alternative to Meds Center provides safe, comfortable and careful tapering methods for clients seeking to withdraw from medications such as Depakote. 

It is fundamental to success that the client's sleeping and eating patterns can be improved as well as adjusting and stabilizing their neurochemistry well before their taper begins. Throughout the withdrawal phase, many other therapies can assist the client in mitigating the above referenced adverse effects, so the titration process is made as comfortable as possible. Our caring clinical and medical teams are dedicated to monitoring and oversight, to ensure the best outcomes possible for our clients. 

We use sauna, massage, mild exercise, chelation, acupuncture, nebulized glutathione treatments, and many other types of therapies that support the client's progress throughout the process. Counseling is also available during the program as well as ample peer support. As nutritional support is key to healthy healing, meals are prepared using mostly organic, fresh local ingredients, deliciously prepared by our goumet chef. 

Find Out More About the Alternative to Meds Center

Find out more about our luxurious world-class facility and all the help that is available to you or your loved one today, by calling and speaking to our well-informed and helpful staff. You don't have to continue to suffer alone. Find out how quickly you can enroll in our Depakote withdrawal program and gain relief from debilitating Depakote side effects.  


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