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Wellbutrin Addiction

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Medically Reviewed

Last Updated on March 30, 2022 by Carol Gillette

Alternative to Meds Editorial Team
Medically Reviewed by Dr Samuel Lee MD

At the Alternative to Meds Center drug addiction treatment facility, we offer Wellbutrin addiction help that allows individuals to be free of this medication and get relief from the overwhelming and serious side effects. Wellbutrin addiction is a growing problem that needs strategic and evidence-based treatment.1

How Does Wellbutrin Addiction Develop?

The path toward Wellbutrin addiction symptoms is similar to any other addiction to a drug, whether legally or illegally sourced. After taking a drug every day for an extended period of time the CNS and brain adapt and become dependent for normal function upon the drug being present. Wellbutrin is FDA approved as an antidepressant, and for smoking cessation. Its molecular structure is similar to amphetamines7 which are highly prone to addiction and abuse. Pharmaceutical ads say that Wellbutrin is believed to restore chemical balance within the brain and this can help with quitting smoking, or feeling less depressed. When used as a smoking cessation tool, studies have shown little to no difference between the placebo and the control groups.8 For more than 3 decades drug advertisements have used this chemical imbalance theory to successfully increase sales of antidepressants, drugs to quit smoking, and many other types of medications.

While the theory sounds like a good thing, researchers have questioned the basis for it, noting that mental health outcomes have not improved during this period despite escalating use of prescribed antidepressants.2-4 Drug regulators also state that they don’t actually know how SSRI drugs like Wellbutrin work.5 What we do know that is actually happening is that the drug is now continuously acting on the dopamine and norepinephrine receptors. The drug will eventually decrease both the volume of neurochemicals in the CNS and brain, and also impair the ability of the receptors along the nerve pathways (that exist all through the body) to respond in normal ways. This is the anatomy of addiction. Restoring a healthy gut (second brain) is also an area of great interest and importance in recovery from Wellbutrin addiction. A healthy gut is needed for natural mental health and well-being.6

wellbutrin effects on central nervous systemAfter addictive neuroadaptation has occurred, when a dose of this drug is missed, delayed, or forgotten; users report Wellbutrin withdrawal symptoms.

Adding fuel to the fire, original symptoms, no longer suppressed, will also return, usually more intense. This leads to needing the drug to dampen these uncomfortable symptoms.

This repeating cycle, reinforced by a poor diet, poor sleep, and lack of exercise among other factors, is typically the pattern of how Wellbutrin addiction develops.

Now let’s look at ways to reverse this dwindling cycle of addiction.

Are There Other Ways to Treat Depression Besides Addictive Drugs like Wellbutrin?

If you are relying on a drug to make you happy every day and make your depression go away, you may feel dependent upon the drug to do these things for you rather than having to do them yourself. There has been much research done since Wellbutrin and other drugs came to the consumer marketplace that tells us there can be many reasons linked to depression, none of which could be classified as a deficiency of medication. There are many more ways to authentically treat depressive symptoms that don’t include addictive drugs like Wellbutrin.

The first step in treating depression should be investigating the sources of such symptoms. Rarely is this ever done before writing a prescription.

Here are some examples of some things that can contribute to or cause a depressed state:

  • Loss, other psychological trauma (present and past unresolved)
  • Bad diet
  • Toxic exposure
  • Poor sleep
  • An unfulfilling lifestyle or career
  • Lack of exercise
  • Lack of sunshine or light
  • Nutritional deficiencies such as magnesium, omega-3 fatty acids
  • Recreational alcohol or drug use
  • Lack of adequate hydration

We may do well to focus on addressing the root causes in solving depression and other ills, but to do this takes longer than a 5-minute visit to a doctor’s office. In the words of the famous author and philosopher GK Chesterton, “It isn’t that they cannot find the solution, it is that they cannot see the problem.”

One could say that spending enough time to properly diagnose a problem is the fastest route to solving it. You can find more detailed information on the website on non-pharmacological alternatives to antidepressant medications that are used at the Alternative to Meds Center.

Holistic Tools to Beat Wellbutrin Addiction

Traditional modes of addiction treatment include counseling, both individual and group or family settings. Learning methods of self-regulation and self-directed lifestyle changes as in CBT or ILM therapies have proven efficacy as psychological models of treatment.8,9

Another set of holistic treatment choices could draw on elements of Chinese traditional medicine, including mindfulness meditation, acupuncture, yoga, Qi Gong

Other effective tools to consider:

  • Dance and movement therapies, exercise 10,11
  • Art therapy
  • Music therapy 12
  • Equine therapy
  • Recreation and leisure, forest bathing and immersion in nature 13
  • Spiritual growth and development, mindfulness-based addiction treatment14

About Wellbutrin Addiction Recovery

Have you experienced Wellbutrin addiction or dependence? Do you seek an authentic recovery? Withdrawing from this drug could be one of the best choices you ever make. But there will be work to do to make improvements that can have lasting positive effects on your life and maybe those around you as well.

Once you slowly begin removing the medication from your system and reach a stable point, you can begin working on yourself, with an aim to understand more about the symptoms that led you to be taking this drug in the first place.

At Alternativ to Meds, it is fundamental to do testing for nutritional deficiencies, to check for accumulations of neurotoxic material over a lifetime, gently purge these from the body, and check for other possible underlying causes and contributors to your depression. Many modes of counseling are provided such as CBT and Life Coaching. Exercise programs and outdoor activities such as Equine therapy are scheduled to boost your body’s production of hormones, energy, and to improve sleep and mood. Spa services are provided such as sauna, colon hydrotherapy, therapeutic massage, nebulized glutathione treatments, IV therapy, and more. We will help you learn what nutritional changes are needed, and why, and also teach you new de-stressing and other life skills that can help you to maintain natural mental health without relying on medication. If you took Wellbutrin to quit smoking, we have a wonderful smoking cessation segment to the program you may benefit from.

We give you the tools to fully resolve Wellbutrin addiction.

If you have these tools, you will discover that prescription drugs are not needed to maintain natural mental health, or find joy in life. After safe withdrawal from Wellbutrin, you can use these tools for the rest of your life. You can recover from addiction to Wellbutrin, and regain the skills you need to build the life that you want to live, free of addiction or dependency on prescription drugs.

The Alternative to Meds Program for Wellbutrin Addiction Treatment

wellbutrin addiction treatment sedona arizonaAt our drug rehab, we search for the underlying causes of why a person is depressed. To fight depression while the drug is withdrawn from the system, we employ targeted amino therapy and specific supplements designed to help produce serotonin. Our program also uses lab tests, natural substances to stabilize the neurochemistry, removal of accumulated toxins, support of peers and a highly trained, compassionate medical and clinical staff, yoga, Qi Gong, holistic pain management techniques, and other resources that provide comforting addiction treatment.

We invite you to call so you can talk to us and achieve an increased understanding of the different types of Wellbutrin addiction help available for you or your loved one.


1. Stall N, Godwin J, Juurlink D. Bupropion abuse and overdoseCMAJ. 2014;186(13):1015. doi:10.1503/cmaj.131534 [cited 2022 Mar 29]

2. Huecker MR, Smiley A, Saadabadi A. Bupropion. [Updated 2021 Oct 17]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470212/ [cited 2022 Mar 29]

3. Baughman F. There is no such thing as a psychiatric disorder/disease/chemical imbalancePLoS Med. 2006;3(7):e318. doi:10.1371/journal.pmed.0030318 [cited 2022 Mar 29]

4. Deacon BJ. The biomedical model of mental disorder: a critical analysis of its validity, utility, and effects on psychotherapy research. Clin Psychol Rev. 2013 Nov;33(7):846-61. doi: 10.1016/j.cpr.2012.09.007. Epub 2013 Apr 8. PMID: 23664634. [cited 2022 Mar 29]

5. FDA label Wellbutrin (bupropion hydrochloride) tablets approval 2003 [cited 2022 Mar 29]

6. Clapp M, Aurora N, Herrera L, Bhatia M, Wilen E, Wakefield S. Gut microbiota’s effect on mental health: The gut-brain axisClin Pract. 2017;7(4):987. Published 2017 Sep 15. doi:10.4081/cp.2017.987 [cited 2022 Mar 29]

7. Tracey JA, Cassidy N, Casey PB, Ali I. Bupropion (Zyban) toxicity. Ir Med J. 2002 Jan;95(1):23-4. PMID: 11928786. [cited 2022 Mar 31]

8. Simon JA, Duncan C, Huggins J, Solkowitz S, Carmody TP. Sustained-release bupropion for hospital-based smoking cessation: a randomized trial. Nicotine Tob Res. 2009 Jun;11(6):663-9. doi: 10.1093/ntr/ntp047. Epub 2009 Apr 24. PMID: 19395688. [cited 2022 Mar 30]

9. Roos CR, Kober H, Trull TJ, MacLean RR, Mun CJ. Intensive longitudinal methods for studying the role of self-regulation strategies in substance use behavior change. Curr Addict Rep. 2020 Sep;7(3):301-316. doi: 10.1007/s40429-020-00329-5. Epub 2020 Aug 13. PMID: 33510995; PMCID: PMC7837607. [cited 2022 Mar 30]

10. Breslin KT, Reed MR, Malone SB. An holistic approach to substance abuse treatment. J Psychoactive Drugs. 2003 Apr-Jun;35(2):247-51. doi: 10.1080/02791072.2003.10400006. PMID: 12924747.[cited 2022 Mar 30]

11. Morris L, Stander J, Ebrahim W, Eksteen S, Meaden OA, Ras A, Wessels A. Effect of exercise versus cognitive behavioural therapy or no intervention on anxiety, depression, fitness and quality of life in adults with previous methamphetamine dependency: a systematic review. Addict Sci Clin Pract. 2018 Jan 16;13(1):4. doi: 10.1186/s13722-018-0106-4. PMID: 29338767; PMCID: PMC5771022. [cited 2022 Mar 30]

12. Witusik A, Pietras T. Music therapy as a complementary form of therapy for mental disorders. Pol Merkur Lekarski. 2019 Dec 27;47(282):240-243. PMID: 31945027. [cited 2022 Mar 30]

13. Antonelli M, Barbieri G, Donelli D. Effects of forest bathing (shinrin-yoku) on levels of cortisol as a stress biomarker: a systematic review and meta-analysis. Int J Biometeorol. 2019 Aug;63(8):1117-1134. doi: 10.1007/s00484-019-01717-x. Epub 2019 Apr 18. PMID: 31001682.[cited 2022 Mar 30]

14. Garland EL, Howard MO. Mindfulness-based treatment of addiction: current state of the field and envisioning the next wave of researchAddict Sci Clin Pract. 2018;13(1):14. Published 2018 Apr 18. doi:10.1186/s13722-018-0115-3 [cited 2022 Mar 30]


Originally Published by Diane Ridaeus Published Nov 4, 2019


This content has been reviewed and approved by a licensed physician.

Dr. Samuel Lee

Dr. Samuel Lee is a board-certified psychiatrist, specializing in a spiritually-based mental health discipline and integrative approaches. He graduated with an MD at Loma Linda University School of Medicine and did a residency in psychiatry at Cedars-Sinai Medical Center and University of Washington School of Medicine in Seattle. He has also been an inpatient adult psychiatrist at Kaweah Delta Mental Health Hospital and the primary attending geriatric psychiatrist at the Auerbach Inpatient Psychiatric Jewish Home Hospital. In addition, he served as the general adult outpatient psychiatrist at Kaiser Permanente.  He is board-certified in psychiatry and neurology and has a B.A. Magna Cum Laude in Religion from Pacific Union College. His specialty is in natural healing techniques that promote the body’s innate ability to heal itself.

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Wellbutrin Addiction
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