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Substance Induced Mania

About Substance-Induced Mania

substance induced maniaThe most common examples of this condition today are mania symptoms that occur during or after ingesting a drug. There are examples of mania or psychosis or other drug-induced symptoms that occur after taking prescribed medications as well as street drugs. The phenomenon can happen after one time, or after a period of regular use, or after becoming addicted to a drug.

In the case of mania, the substance-induced high is usually followed by a crash. Hence many addicts have come to be diagnosed with bipolar1 as that pattern would seem to fit the criteria as laid out in the DSM. The usual mania treatment once diagnosed is to drug the patient with sedatives, antipsychotics, or other pharmaceutical drugs. However, if the actual addiction and risky behavior have not been curtailed in treatment, there is no drug in the world that will cure the highs and lows of drug addiction. Like pouring gasoline on a fire, it does not alleviate and can in fact exacerbate the factors that led to the manic state.

Mania can be made worse with the use of certain medications.

Substances Known to Cause Mania or Psychosis:

  • Cocaine *
  • LSD *
  • Marijuana
  • Medications for Parkinson’s Disease *
  • Antidepressants
  • Anticonvulsants
  • Amphetamines/methamphetamine
  • Muscle Relaxants
  • Stimulants 

* In the DSM 5,  substance-induced psychosis (i.e. psychosis while on antidepressants) attempts to narrowly define the condition as Bipolar 1, a mental illness requiring further drug treatment.  However, there has been controversy on the subject of the diagnosis and best treatment of psychosis. Some medical literature observes the symptoms usually subside after the substance is cleared from the body. 2,3

Treatment for Substance-Induced Mania

drug-induced psychosis

Although substance-induced mania may seem difficult to overcome, such symptoms related to mania can be addressed and corrected safely with non-harmful protocols.

Mania (from the Greek root which means “addiction to”) has come down the centuries to mean in current psychiatric verbiage, a condition lasting at least one week of heightened enthusiasm, euphoria, inability to sleep, and elevated self-esteem. Other characteristics have come to be added to the list, over time.

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Alternative to Meds Center’s Holistic Approach to Drug-Induced Mania, Psychosis, etc.

Restoring Your Brain ChemistryIf one has suffered from substance abuse which resulted in a manic state that was interpreted as bipolar or another mental illness diagnosis, and the treatment received for it did not handle the situation satisfactorily, one can call us at Alternative to Meds Center.

One owes it to oneself to find out what other methods of treatment are available. Alternative to Meds Center knows that it is possible to recover one’s health and to also sustain the mental clarity and balance achieved through a sound treatment process, rather than the typical knee-jerk treatment of labeling and then drugging the patient.

Please call us at the center to find out more about how we treat substance-induced mania and other mental health issues using non-harmful protocols. 

  1. Terao T, Teruaki T,  “Antidepressant-induced mania or hypomania in DSM 5.” Psychopharmacology 231, 315 (2014). https://doi.org/10.1007/s00213-013-3358-4 [cited September 14, 2020]
  2. Breggin P, “Solutions to madness and personal crises.”  August 2013 [Internet] Psychiatric Drug Facts [cited September 14, 2020]
  3.  Tamminga C,  “Substance/Medication-Induced Psychotic Disorders.” Merck Manual for Consumers [Internet] May 2020 [cited September 14, 2020]


This content has been reviewed and approved by a licensed physician.

Dr. Samuel Lee

Dr. Samuel Lee is a board-certified psychiatrist, specializing in a spiritually-based mental health discipline and integrative approaches. He graduated with an MD at Loma Linda University School of Medicine and did a residency in psychiatry at Cedars-Sinai Medical Center and University of Washington School of Medicine in Seattle. He has also been an inpatient adult psychiatrist at Kaweah Delta Mental Health Hospital and the primary attending geriatric psychiatrist at the Auerbach Inpatient Psychiatric Jewish Home Hospital. In addition, he served as the general adult outpatient psychiatrist at Kaiser Permanente.  He is board-certified in psychiatry and neurology and has a B.A. Magna Cum Laude in Religion from Pacific Union College. His specialty is in natural healing techniques that promote the body’s innate ability to heal itself.

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